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The binding of cyanide to cytochrome c oxidase prevents transport of electrons from cytochrome c to oxygen in the mitochondria.As a result, the electron transport chain is disrupted, meaning that the cell can no longer aerobically produce ATP for energy. The central nervous system and the heart, are particularly affected.
Oral ingestion of a small quantity of solid cyanide or a cyanide solution as little as 200 mg, or to airborne cyanide of 270 ppm is sufficient to cause a very painful death within minutes.

The binding of cyanide to cytochrome c oxidase prevents transport of electrons from cytochrome c to oxygen in the mitochondria.
As a result, the electron transport chain is disrupted, meaning that the cell can no longer aerobically produce ATP for energy.
The central nervous system and the heart, are particularly affected.


Oral ingestion of a small quantity of solid cyanide or a cyanide solution as little as 200 mg, or to airborne cyanide of 270 ppm is sufficient to cause a very painful death within minutes.
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Which oxygen dependent tissues are severely affected by acute cyanide poisoning?

The tissues most severely affected by acute cyanide poisoning are the brain and the heart. This is because both organs have high oxygen demands and rely heavily on aerobic metabolism. Cyanide inhibits the enzyme cytochrome c oxidase in the electron transport chain, disrupting cellular respiration and leading to rapid cell death in these tissues.


Which oxygen dependent tissues are affected by acute cyanide poisoning?

Brain liver heart


What oxygen-dependent tissue is severly affected by acute cyanide poisoning?

Liver, Spleen & Brain (Not the kidneys)


Does cyanide poisoning look like heart disease?

No, cyanide poisoning stop the respiration .


Which cellular organelle would be affected by cyanide poisoning?

Mitochondria are the cellular organelles that would be affected by cyanide poisoning. Cyanide inhibits the enzyme cytochrome c oxidase, which is involved in the electron transport chain in the mitochondria. As a result, cells are unable to produce ATP, leading to cellular dysfunction and eventual cell death.


Is atropine an antidote for cyanide?

No, atropine is not an antidote for cyanide poisoning. The primary antidotes for cyanide include hydroxocobalamin and sodium thiosulfate. Atropine is an anticholinergic medication used to treat bradycardia and certain types of poisoning, but it does not counteract the effects of cyanide.


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Symptoms of cyanide poisoning in dogs may include difficulty breathing, seizures, vomiting, diarrhea, and sudden collapse. Immediate veterinary attention is crucial if poisoning is suspected.


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What are the signs of cyanide poisoning in dogs?

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Which of the following is a cyanide antidote Nitrite CANA Atropine 2-prolidoxime chloride?

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