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Where is the beta globin gene?
The beta globin gene is located on chromosome 11 in humans. It codes for the beta globin protein, which is a subunit of hemoglobin found in red blood cells. Mutations in this gene can lead to conditions such as sickle cell anemia and beta thalassemia.
What chromosome is the HBB gene on?
The HBB gene, which codes for the beta globin protein, is located on chromosome 11.
The genotype of the person with normal red blood cells is?
The genotype of a person with normal red blood cells is usually AA, where both copies of the beta-globin gene are normal. This results in the production of normal hemoglobin and red blood cells.
What is the mRNA sequence for a person with sickle cell anemia?
For sickle cell anemia, there is a single-point mutation in the beta-globin gene. The mutation causes a change in the mRNA sequence from GAG to GTG, resulting in the substitution of glutamic acid with valine at the 6th position of the beta-globin protein.
Adenine and thymine mutation in sickle cell?
yes. thymine replaces adenine in the dna that codes for the amino acid on the 6th position of the beta globin chain resulting in an amino acid change of glutamic acid to valine. shari (med student - jamaica)
Where is the beta globin gene?
The beta globin gene is located on chromosome 11 in humans. It codes for the beta globin protein, which is a subunit of hemoglobin found in red blood cells. Mutations in this gene can lead to conditions such as sickle cell anemia and beta thalassemia.
What chromosome holds the gene for beta globin?
Chromosome 11
What chromosome is the HBB gene on?
The HBB gene, which codes for the beta globin protein, is located on chromosome 11.
The genotype of the person with normal red blood cells is?
The genotype of a person with normal red blood cells is usually AA, where both copies of the beta-globin gene are normal. This results in the production of normal hemoglobin and red blood cells.
Is sickle cell anemia an autoimmune disease?
Sickle Cell Anemia is Autosomal Recessive. It arises from a mutation on the beta-globin gene of chromosome 11. Because Sickle Cell Anemia is an example of incomplete dominance, a person has the disease if they have two mutated beta-globin genes but only has the trait (is a carrier) if they have only one mutated beta-globin gene.
What is the mRNA sequence for a person with sickle cell anemia?
For sickle cell anemia, there is a single-point mutation in the beta-globin gene. The mutation causes a change in the mRNA sequence from GAG to GTG, resulting in the substitution of glutamic acid with valine at the 6th position of the beta-globin protein.
Adenine and thymine mutation in sickle cell?
yes. thymine replaces adenine in the dna that codes for the amino acid on the 6th position of the beta globin chain resulting in an amino acid change of glutamic acid to valine. shari (med student - jamaica)
Why is a specific region of chromosome 11 referred to as the globin gene cluster?
Due to its relation with formation of globin.
What mutations does beta-thalassemia have on DNA?
Beta-thalassemia is typically caused by mutations in the HBB gene located on chromosome 11. Common mutations include point mutations, deletions, or insertions in the HBB gene, leading to reduced or absent production of beta-globin chains in hemoglobin. These mutations disrupt the normal structure and function of hemoglobin, resulting in anemia and other symptoms associated with beta-thalassemia.
My husband and I are Beta thalassemia minors and undergone Mutation analysis in beta globin gene. sequencing report is also awaited. please advice us on our chances of having a baby in this case?
The related links contain the best information I could find.
What is the DNA code for normal hemoglobin?
The DNA code for normal hemoglobin is the gene that encodes for the production of the protein hemoglobin. The sequence of this gene includes instructions for building the alpha and beta globin chains that make up the hemoglobin protein. This gene is located on chromosome 11 in humans.
How many polypeptide chains form the globin portion of the molecule?
4 polypeptide chains, each bound to a heme group to form hemoglobing
