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How many copies of the beta globin gene do people have?
Most individuals have two normal copies of the beta globin gene
What chromosome is the HBB gene on?
The HBB gene, which codes for the beta globin protein, is located on chromosome 11.
What is the mRNA sequence for a person with sickle cell anemia?
For sickle cell anemia, there is a single-point mutation in the beta-globin gene. The mutation causes a change in the mRNA sequence from GAG to GTG, resulting in the substitution of glutamic acid with valine at the 6th position of the beta-globin protein.
What is the molecular formula for Beta-globin?
This question is most commonly asked during the month of October. The molecular formula for beta-globin is: HBA-HBB=scary monster! BOO!
Adenine and thymine mutation in sickle cell?
yes. thymine replaces adenine in the dna that codes for the amino acid on the 6th position of the beta globin chain resulting in an amino acid change of glutamic acid to valine. shari (med student - jamaica)
How many copies of the beta globin gene do people have?
Most individuals have two normal copies of the beta globin gene
What chromosome holds the gene for beta globin?
Chromosome 11
What chromosome is the HBB gene on?
The HBB gene, which codes for the beta globin protein, is located on chromosome 11.
Beta 0 thalassemia a nonsense mutation in man?
Beta 0 thalassemia is a genetic disorder caused by a nonsense mutation in the HBB gene, which encodes the beta-globin subunit of hemoglobin. This mutation leads to a premature stop codon, resulting in the production of nonfunctional or absent beta-globin chains. As a consequence, individuals with beta 0 thalassemia have reduced or absent hemoglobin A (HbA), leading to anemia and a range of related health issues. The severity of symptoms can vary based on the specific genetic mutations and the presence of other globin gene alterations.
Is sickle cell anemia an autoimmune disease?
Sickle Cell Anemia is Autosomal Recessive. It arises from a mutation on the beta-globin gene of chromosome 11. Because Sickle Cell Anemia is an example of incomplete dominance, a person has the disease if they have two mutated beta-globin genes but only has the trait (is a carrier) if they have only one mutated beta-globin gene.
What is the mRNA sequence for a person with sickle cell anemia?
For sickle cell anemia, there is a single-point mutation in the beta-globin gene. The mutation causes a change in the mRNA sequence from GAG to GTG, resulting in the substitution of glutamic acid with valine at the 6th position of the beta-globin protein.
How is hemoglobin constructed?
Normal adult hemoglobin has a pair each of alpha-globin and beta-globin molecules
What is the molecular formula for Beta-globin?
This question is most commonly asked during the month of October. The molecular formula for beta-globin is: HBA-HBB=scary monster! BOO!
Adenine and thymine mutation in sickle cell?
yes. thymine replaces adenine in the dna that codes for the amino acid on the 6th position of the beta globin chain resulting in an amino acid change of glutamic acid to valine. shari (med student - jamaica)
Why is a specific region of chromosome 11 referred to as the globin gene cluster?
Due to its relation with formation of globin.
What mutations does beta-thalassemia have on DNA?
Beta-thalassemia is typically caused by mutations in the HBB gene located on chromosome 11. Common mutations include point mutations, deletions, or insertions in the HBB gene, leading to reduced or absent production of beta-globin chains in hemoglobin. These mutations disrupt the normal structure and function of hemoglobin, resulting in anemia and other symptoms associated with beta-thalassemia.
My husband and I are Beta thalassemia minors and undergone Mutation analysis in beta globin gene. sequencing report is also awaited. please advice us on our chances of having a baby in this case?
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