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One use of radon based on this principle is in leak detection. An isotope of radon is added to a flow of gas or liquid through a tube. A Geiger counter can be passed along the outside of the tube. If radiation is present, the Geiger counter makes a sound or flashes a light. The presence of radiation indicates a leak in the tube. This principle is applied in many other systems to study materials that cannot actually be seen.

Radioactive water baths have been applied since 1906 in Jáchymov, Czech Republic, but even before radon discovery they were used in Bad Gastein, Austria. Radium-rich springs are also used in traditional Japanese onsen in Misasa, Tottori Prefecture. Drinking therapy is applied in Bad Brambach, Germany. Inhalation therapy is carried out in Gasteiner-Heilstollen, Austria, in Świeradów-Zdrój, Czerniawa-Zdrój, Kowary, Lądek Zdrój, Poland, in Harghita Băi, Romania, and in Boulder, United States. In the United States and Europe there are several "radon spas," where people sit for minutes or hours in a high-radon atmosphere in the belief that low doses of radiation will invigorate or energize them.

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