0
Antigen-presenting cells (APCs), primarily dendritic cells, macrophages, and B cells, introduce epitopes to T cells. They process and present peptide fragments of antigens on their surface using major histocompatibility complex (MHC) molecules. This interaction is crucial for T cell activation, allowing them to recognize and respond to specific pathogens or infected cells. Dendritic cells are particularly effective at initiating T cell responses due to their ability to capture and present antigens in lymphoid tissues.
What else can I help you with?
The basic determinating feature of antigenic specificity is ...........?
The basic determining feature of antigenic specificity is the unique structure of antigenic epitopes, which are the specific regions on an antigen recognized by antibodies or T cell receptors. These epitopes interact with corresponding binding sites on antibodies or T cell receptors, leading to the immune response against the antigen.
What is the cells that helps regulate body function?
A large number of cell types participate in the immune reaction, but all of them are derived from the same Hematopoietic Stem Cells.Certain Important Cells are:T Cells (T Lymphocytes): T cells are responsible for the cell mediated immune response. There are two types of T lymphocytes:T Cytotoxic: They are responsible for the cell mediated cytotoxicity.T Helper: They secrete cytokines that activate the T helper cells and macrophages.B Cells (B Lymphocytes): B lymphocytes are responsible for humoral immunity. They secrete antibodies in response to the antigens entering body.Macrophages: They are the major scavengers, as they phagocytocize the antigen and represent the epitopes on their surfaces.Neutrophils: They are associated with inflammation.Dendritic Cells: Dendtritic cells are specialised cells with versatile functions, including antigen capturing and antigen presentation.Natural Killer Cells: They are cells with small population that are active against tumor cells and some but not all virus infected cell.
Which cell produces perforin?
Perforin is produced by cytotoxic T cells (CD8+ T cells) and natural killer (NK) cells. It is used in these cells to induce cell apoptosis in target cells, such as infected or cancerous cells.
What are the 3types of t cells?
The three main types of T cells are: helper T cells, cytotoxic T cells, and regulatory T cells. Helper T cells assist in activating other immune cells, cytotoxic T cells directly kill infected or abnormal cells, and regulatory T cells help control the immune response to prevent excessive reactions.
Which of the following cells is the most critical cell in immunity?
The most critical cell in immunity is the T lymphocyte (T cell). T cells play a key role in coordinating immune responses by recognizing and attacking infected cells and regulating other immune cells.
Properties of Tcell and B cell epitopes?
Properties of B cell epitopes •The size is determined by the size, shape and amino acid residue of the Ag-binding site on the Ab molecule •The binding involves weak non covalent interaction •Native proteins generally hydrophilic amino acids •Sequential or non-sequential amino acids •Located in mobile regions •Accessible Properties of T cell epitopes •T cell recognize Ag that has been processed in antigenic peptides with MHC •Antigenic peptides recognized by T cells form trimolecular complexes with a T cell receptor and MHC molecules •Internal peptides
The basic determinating feature of antigenic specificity is ...........?
The basic determining feature of antigenic specificity is the unique structure of antigenic epitopes, which are the specific regions on an antigen recognized by antibodies or T cell receptors. These epitopes interact with corresponding binding sites on antibodies or T cell receptors, leading to the immune response against the antigen.
What is the cells that helps regulate body function?
A large number of cell types participate in the immune reaction, but all of them are derived from the same Hematopoietic Stem Cells.Certain Important Cells are:T Cells (T Lymphocytes): T cells are responsible for the cell mediated immune response. There are two types of T lymphocytes:T Cytotoxic: They are responsible for the cell mediated cytotoxicity.T Helper: They secrete cytokines that activate the T helper cells and macrophages.B Cells (B Lymphocytes): B lymphocytes are responsible for humoral immunity. They secrete antibodies in response to the antigens entering body.Macrophages: They are the major scavengers, as they phagocytocize the antigen and represent the epitopes on their surfaces.Neutrophils: They are associated with inflammation.Dendritic Cells: Dendtritic cells are specialised cells with versatile functions, including antigen capturing and antigen presentation.Natural Killer Cells: They are cells with small population that are active against tumor cells and some but not all virus infected cell.
Which cell produces perforin?
Perforin is produced by cytotoxic T cells (CD8+ T cells) and natural killer (NK) cells. It is used in these cells to induce cell apoptosis in target cells, such as infected or cancerous cells.
Why does a macrophage place antigens on its surface?
When a macrophage engulfs a foreign antigen, it phagocytizes it (or breaks it down) using enzymes. The fragments (called epitopes) of the original antigen are transported to the cell surface so that helper T-cells that specifically match the antigen can recognize it. When that happens, the helper-T cells are able to trigger a specific immune response to that exact antigen by stimulating more helper-T cells to be produced and by triggering B-cells to secrete antigen-specific antibodies that mark infected cells for destruction by killer T-cells.
What does T cytotoxic cell?
The cytotoxic T cell, when it finds cells displaying the wrong antigens, ruptures the cell membrane of the offending cell killing it. Cytotoxic T cells are effective against virus infected cells and cancer cells.
What are the 3types of t cells?
The three main types of T cells are: helper T cells, cytotoxic T cells, and regulatory T cells. Helper T cells assist in activating other immune cells, cytotoxic T cells directly kill infected or abnormal cells, and regulatory T cells help control the immune response to prevent excessive reactions.
Which of the following cells is the most critical cell in immunity?
The most critical cell in immunity is the T lymphocyte (T cell). T cells play a key role in coordinating immune responses by recognizing and attacking infected cells and regulating other immune cells.
What cells types are specifically responsible for cell mediated immunity?
T cells are specifically responsible for cell-mediated immunity. They include cytotoxic T cells, helper T cells, and regulatory T cells, each playing a crucial role in orchestrating the immune response against pathogens or abnormal cells.
Are cytotoxic T cells a type of T cell clone?
Yes, cytotoxic T-cells are a subset of T-cells that in contrast to helpter T-cells express CD8.
What are the steps in cell mediated immune process?
Antigen presentation: Antigen-presenting cells (APCs) process and present antigens to T cells. T cell activation: APCs activate T cells by binding to their T cell receptors and providing co-stimulatory signals. T cell proliferation and differentiation: Activated T cells undergo clonal expansion and differentiate into effector T cells, such as cytotoxic T cells and helper T cells. Target cell destruction: Effector T cells recognize and kill infected or abnormal cells through various mechanisms, such as releasing cytotoxic molecules or activating other immune cells.
Do helper t cells have a cell membrane?
Yes, helper T cells, like all other cells, have a cell membrane. The cell membrane is a semipermeable barrier that surrounds the cell and helps regulate the passage of molecules in and out of the cell.
