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Before a call membrane can respond to a second stimulus, it must first undergo a process called repolarization, where the membrane potential returns to its resting state after an initial action potential. During this period, known as the refractory period, the ion channels that were activated must reset to their resting state. Only after this process can the membrane be prepared to respond to another stimulus effectively. Additionally, the cellular environment must stabilize to ensure proper ion concentration gradients are restored.

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4mo ago

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