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During the relative refractory period, some voltage-gated potassium channels are still open, causing an outward flow of potassium ions. This outward flow of potassium ions opposes depolarization, making it more difficult to reach the threshold for generating a second action potential. Additionally, some sodium channels may still be inactivated, further limiting the ability to generate another action potential.

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1y ago

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Define the period of repolarization when only a strong stimulus will elicit an action potential?

The period of relative refractory period is the time after an action potential during which a strong stimulus is required to generate a new action potential. This is because the membrane potential is hyperpolarized, making it more difficult to reach the threshold for firing another action potential.


2 Define refractory period and differentiate between absolute and relative refractory periods?

refractory period is the interval between action potential , the absolute refractory period is the period in which second action potential can not be initiated but in relative refractory period the second action potential can be initiated by the more strong stimulus.


What happens during the refractory period?

The voltage-gated Na+ channels get deactivated, thus the sodium ions cannot diffuse into the cell and cause depolarisation and this also provides time for the membrane to prepare for its second action potential.


What is the relationship between the absolute and relative refractory periods during the action potential process?

During the action potential process, the absolute refractory period is when the neuron cannot respond to any stimulus, while the relative refractory period is when it can respond to a stronger stimulus. The absolute refractory period comes before the relative refractory period in the action potential process.


Absolute refractory period relative refractory period?

In absolute refractory period, none of channels are reconfigured, so that second active potential cannot be generated no matter how large the stimulus current is applied to the neuron. In contrast, in relative refractory period, some but not all of channels are reconfigured, another action potential can be generated but only by a greater stimulus current thatn that originally needed.


What is the relationship between the absolute and relative refractory periods in the context of neuronal excitability?

The absolute refractory period is the time when a neuron cannot generate another action potential, regardless of the stimulus strength. The relative refractory period is the time when a neuron can generate another action potential, but only with a stronger stimulus. These periods help regulate neuronal excitability by ensuring that neurons fire in a controlled manner and prevent excessive firing.


When do you use relative refractory period?

The relative refractory period is the time during which the generation of an action potential is impossible no matter the strength of the stimulus


How does threshold change during the relative refractory period?

During the relative refractory period, the threshold for excitation is increased compared to the resting threshold. This is because the membrane potential is closer to its resting state, making it more difficult to depolarize the cell and generate an action potential. It requires a stronger stimulus to overcome this increased threshold and trigger another action potential.


What is the cause of the relative refractory period?

The Refractory period is when a second action potential is possible, but unlikely; second action potential only if the stimulus is sufficiently strong. The refractory period helps to prevent backflow of Sodium.


During which period can a second action potential be initiated by a larger than normal stimulus?

The period following the absolute refractory period is where a second action potential can be initiated by a larger than normal stimulus. This phase is known as the relative refractory period.


What is The time an action potential begins until the resting potential has stabilized is?

1/2500 sec is the absolute refractory period.


What is the period of time during which the neuron cannot generate another action potential called?

refractory period