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The activation gates of voltage-gated Na+ channels open, and Na+ diffuses into the cytoplasm.

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What opens first in response to threshold stimulus?

The activation gates of voltage-gated Na+ channels open, and Na+ diffuses into the cytoplasm.


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Even if a stimulus triggers an all-or-none response, the level of pain experienced can vary depending on individual differences in pain perception, tolerance, and other factors like emotional state or context in which the pain occurs. Each person's perception and experience of pain can be influenced by a variety of factors beyond just the specific stimulus.


How can I effectively perform a door threshold repair to ensure the durability and functionality of my entryway?

To effectively perform a door threshold repair for a durable and functional entryway, follow these steps: Remove the old threshold carefully. Clean the area thoroughly to remove any debris or old adhesive. Measure and cut the new threshold to fit the doorway. Apply a waterproof sealant to the bottom of the new threshold before installing. Secure the new threshold in place using screws or adhesive. Test the door to ensure it opens and closes smoothly. Apply a final coat of sealant to protect the threshold from moisture and wear.


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