There are so many answers in this thread it is baffling. Some of the answers are accurate, semi-accurate and some are just down right wrong. It all depends on what test is used. The most widely used lateral flow immunoassays are calibrated for oxazepam at 300 ng/ml of urine. If it is positive they generally send it off for GC/MS testing. As someone already clearly stated what clonazepam breaks down to it would be redundant for me to do into that. Clonazepam does not metabolize to oxazepam. However, large doses over a period of time can lead to a positive immunoassay, ususally around 781 ng/ml of Clonazepam. The amount of actual non-metabolized clonazepam released in urine is less than 1-2%.

In a chronic low-dose user (less than 3mg per day), many test negative on immunoassay. Single dose users, dependent on dose generally test negative on immunoassays. If an immunoassay is calibrated toward 7-aminoclonazepam and clonazepam (they are available) they would produce a positive.

When expensive GC/MS testing is done due to a positive BZO lateral flow, the lab needs to know to look for Clonazepam and 7-amino clonazepam.

In sum, if someone stays off clonazepam for a few days, the likelyhood of a positive test by most used lateral flow immunoassay would be very slim. So, it would techinally would be a "false-negative" because the lab could detect it if looking for it with GC/MS. There is much literature online one can review. Academic literature is more accurate than others info. Alot of what people put out there is incorrect and/or incomplete.

Answer:

The short answer is: Stop taking the drug and wait. It'll be gone in a few days.

The catch is that, like all benzodiazipam category drugs, if you've been taking it for more then a month then you'll need to taper off slowly because of withdrawals (although extremely rare, 2 deaths have been attributed2).

Answer:

Not only can a drug test detect Klonopin, it can also measure the level, or amount of drug in the body.

Answer:

Klonopin® (generic: Clonazepam) is a benzodiazapine used to treat anxiety and panic disorders. It has a half-life of anywhere from 18-50 hours, meaning that is how long it takes your body to reduce the amount of clonazepam in your system by half.

If you took three 1 mg tablets, within one to two days, 50% of its major metabolite 7-aminoclonazepam (7-ACLO) will still be in your system, and detectable by urinalysis; within three to four days, 75% of the metabolite will have cleared; within five to six days, 87.5% will have cleared, and so on.

Unfortunately, because the rate of metabolism varies from person to person, the concentration of 7-ACLO measurable in the urine doesn't necessarily decline in a direct linear fashion. You may show peak concentration, the point at which the metabolite is highest and most easily detected, anywhere from the first to the eighth day after taking the drug. Depending on the sensitivity and specificity of the test, one 3 mg. dose of clonazepam is detectable in urinalysis at 14 days; and there is a 75-80% chance of it being detectable at 21 days. It may take 28-30 days for the medication to clear your body completely.1

Most likely, a low-cost employment or other screening test won't be sensitive enough to pick up the one-time use anywhere near that long (the above data came from a forensic study). A drug detection timetable for short-term use of benzodiazapines suggests you should be able to pass a drug test after 5-7 days (the upper end of the time line). This is not a guarantee, however.

Since benzodiazepines are metabolized by the liver and excreted in the urine, drinking a lot of water may help slightly, but won't increase the speed at which your body metabolizes the drug.

This information is intended for educational purposes only and should not be considered medical advice.

1 Elimination of 7-aminoclonazepam in urine after a single dose of clonazepam

2 Source: http://journals.lww.com/amjforensicmedicine/Abstract/2009/06000/A_Fatal_Case_of_Benzodiazepine_Withdrawal.14.aspx

Accudiagnostics

I will do further checking of the medical journals later and repost my reply. I have been taking 4mg of Clonazepam (Klonopin) since my auto accident in 2006, when my car flipped, rolled 3 times, my airbag did not deploy, my seat-belt was on, and I had a fractured skull, vertebrae, and 5th metatarsal. I have Cerebral Palsy, which was mild until my accident. After my accident, I developed hammer toes and increased shakiness, etc. My doctor prescribed this medication and kept increasing the does until the problems that kept me from functioning and sleeping disappeared (yes, she was amazed that I tolerated the dosage without falling asleep in her office). A little less than 3 years ago, I moved to PA and found a new physician. I take 2mg of Clonazepam around 6A.M. and see my doctor in the afternoon and ALWAYS fail the urine test. I am researching to discover why (I am uncertain as to what type of urine screen they do, but was assured that it should show up in my urine). This has caused me a great deal of difficulty but one day, after my doctor's staff did not give her my messages about refilling my Rx (they were buried under papers on top of my file), I showed up at her office in withdrawal (my BP was around 160/130 something and pulse was in the 120s, and I felt awful. I can guarantee you that 8 hours after taking 2mg of Klonopin/Clonazepam that it did not show up in the urine tests. I am dealing with a new doctor at this clinic since November, and was told Wednesday (after calling about my refill Friday, Monday and Tuesday) that they would not refill my Rx, would not do any further tests and wanted to see me in 3 months. I requested a copy of my medical records, went to the ER (my BP was up again), I failed the urine test there, they gave me 2mg last night, watched me take it, checked my mouth (all at my request) and I am returning for another test this morning, which I know I will fail again.

"Insensitivity of benzodiazepine screen: only 40% for lorazepam; clonazepam (Klonopin) frequently negative on both EIA and GCMS."

Source: http://www.med.umich.edu/1info/FHP/practiceguides/pain/drugtesting.pdf

Klonopin, also known as Rivotril (clonazepam) is a benzodiazepine class sedative/hypnotic and anticonvulsant. It is similar to medications like Valium (diazepam), Xanax(alprazolam), and Ativan (lorazepam).

Clonazepam is primarily used to treat anxiety disorders, especially panic disorder. Only Klonopin and Xanax are FDA approved benzodiazepines for treatment of panic disorder with or without agoraphobia. Klonopin is commonly used to treat other anxiety problems, agitation, acute mania (in conjunction with other drugs), and for acute seizure control. It is occasionally used as a long term anticonvulsant, as a sleeping pill, and for the treatment of neuropathic (nerve) pain.

After taking Klonopin people tend to feel relaxed and a little tired. Side effects vary widely from person to person and depend on the dose. For anxiety Klonopin is typically prescribed between 0.25 mg- 2 mg twice daily. For epilepsy doses may go as high as 20 mg/day.

Klonopin acts on the neurotransmitter GABA, an inhibitory chemical. Through complex actions Klonopin effectively reduces the ability of nerves to fire, slowing down the brain. As a result of the reduced activity, anxiety is reduced, people become tired, and the reduction of nerve firings reduces the chance of seizure or can help stop a seizure in progress.

If you are asking in terms of legitimate medical treatment, then this is a question only your doctor can answer. All three of these drugs are benzodiazepines, which means they are similar, yet ultimately have different usages and effects. Which one is best for you to take is a matter that only you and your doctor can decide. It depends on your physiological, psychological, and neurological makeup. Depending on your medical needs and history, any of the three could be best. In order to determine which is best for you, you would have to undergo medical and psychiatric evaluation, and possibly also a trial period for each, to see which one works better for you personally.

If you are asking in terms of recreational use, then I would say Valium is best, although Xanax is a very close runner-up. Valium tends to work faster, hit harder, and leave your body more quickly, so it will give you the best immediate high, without the lingering effects that you may not want (such as grogginess, sleepiness, headaches, or inability to concentrate).

The effects of Xanax are less rapid and intense, but the effects last 2 or 3 times as long. This is good if you want to enjoy some residual effects the next day, but it's bad if you have to get up early to work or study or play sports.

Klonopin is the worst of the three. As far as I can tell, it does absolutely nothing but make you sleep for 24 to 36 hours straight (depending on your dosage and body size). In my experience, there is NO high from Klonopin. It's just a powerful sleeping pill. However, my experience with it was not recreational. I was a severe alcoholic at the time (roughly 1 liter of vodka every day), so when I finally got help and detoxed, the Klonopin was prescribed to prevent the life-threatening seizures that accompany alcohol withdrawal. For people who are not detoxing alcoholics, the effects may be very different.

Here is the bottom line: with the sole exception of marijuana, there is ALWAYS a risk in taking recreational drugs, so you must always be careful, use your common sense, listen attentively to your body, and respect its limitations. Don't overdo it. And if you consistently find yourself overdoing it and repeatedly getting totally out of control on drugs, making a fool of yourself and hurting the people around you...well, then these drugs are obviously not for you. Maybe you should switch to a drug that is neither physically nor chemically addictive, namely, marijuana.

Of course, marijuana can be addictive too, but only "psychologically addictive." Which is just a fancy word for "habit forming."

The point is, if drugs are negatively affecting your life -- your job, your relationships, your finances, your hopes and dreams -- then you're not the type of person who can handle drugs. And there is no shame in this. It's not a reflection on your character or your mental strength. It's just the way some humans develop. It's the way you were born and raised. It's nature and nurture: you're born with certain genetic traits that are beyond your control, and they are reinforced by your parents and close relatives.

It takes a tremendous amount of personal strength and self-awareness to overcome addiction. Addiction is a disability just like any other, and you have to learn -- slowly, painfully -- to function and live a healthy life regardless of your addictive nature. The only shame is in not trying to help yourself.

If you insist on using Valium, Xanax, or Klonopin recreationally, then PLEASE BE VERY CAREFUL not to take too much. Don't swallow multiple pills at once, ESPECIALLY if you are an inexperienced user. You could easily pass out and never wake up again. When taken without supervision, these drugs can be very dangerous. It is highly, HIGHLY recommended that you have someone with you who can call 911 if you begin to have problems.

If you are a brand-new user, start with a 1 mg dose (1/2 of a 2mg pill, or about 1/4 of a 5mg pill). Wait 30 to 40 minutes to see how it affects you. If there is little or no effect, then take another 1 milligram, and wait another 30 minutes. You can continue on from there. Taking the drugs slowly and gradually gives your body time to adjust and process what is going on. It will also allow enough time for your body to warn you that, "I can't take much more of this without keeling over. Stop NOW."

The previous answer does have some valid points. Valium is a medium lasting benzo. Therfore, it takes longer to leave your system than Xanax, which is an extremely short acting benzo.

While the above answer does have some good advice, the author's knowledge of how these drugs work is a bit inaccurate. I have 40 years of experience with benzos, and I don't want someone to take this person's advice regarding Valium verses Xanax, and wind up messed up for a lot longer than they expected!

Someone is really looking for a trip to the Psyche ward with a possible ending at the morgue. Take what is prescribed for you, the possible side effects and negative interactions have been taken into consideration by your physician.

Adderall helps my Cymbalta, leave that other stuff alone.