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Europeans sought to establish trade in East Asia primarily through the establishment of missions aimed at converting local populations to Christianity while simultaneously fostering economic ties. The Spanish focused on the Philippines, using it as a base for trade with China and Japan, and missionaries like the Jesuits played a key role in cultural exchange. The Portuguese established trade routes in the 16th century, particularly around Macau, facilitating commerce with China. Overall, European powers combined religious missions with mercantile interests to secure their foothold in the region.

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