You can fit a SBC in an S-10 you need a kit to do it though.
http://www.s10v8.com/store/index.php/cPath/21?osCsid=11e71117ba764235a8676073622a721d
NO. Not even close.
no
A small block Chevy engine will fit into a 88 S10 with the help of some adapters.
Will a Chevy blazer engine fit in a Chevy s10 pickup
Google "Jegs"
In place of the coolant drain plug on either side of the block.
Yes
Will a Chevy Blazer engine fit in a Chevy s10 pickup
Which model of Chevy? Huge difference between an S10 and a Top Kick.
Yes
NO.
NO it will not.