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No, end plate current of excitatory post-synaptic current(EPSC) represents the sum of the currents through thousands of AChRs in the postsynaptic membrane. The end-plate potential or Excitatory post-synaptic potential(EPSP) is the local depolarisation at the post-synaptic membrane which eventually results in an action potential at the postsynaptic membrane of the neuromuscular junction. EPSP is much slower than the EPSC because of the time necessary to charge and discharge the capacitance of the muscle membrane.
Hope this helps, there is a lot more detail in the notes we were given which I'll be happy to share if you need it.
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A folded region of the sarcolemma at the neuromuscular junction?
At the neuromuscular junction (or presynaptic end) of the sarcolemma, it is referred to as end plate synapse potential.
What happens to the muscle membrane when acetylcholine binds to receptors at the motor plate?
When acetylcholine binds to receptors at the motor plate, this binding opens ligand-gated ion channels on the motor end plate, ions diffuse through the open ligand gated ion channels, and the flow of ions causes the motor end plate to reach threshold and an action potential is generated at the motor end plate.
What change does ACh cause in an ACh receptor?
ACh binds to each ACH receptor which causes opening of ligand-regulated ion gate and the creation of end-plate potential.
Are end plate osteophytosis and osteoarthritis the same thing?
I do not know, but I am guessing not, considering there had two different names. Just a thought.
What is the anterior-inferior end plate?
the Vertebral end plate is the section of the vertebra that in faces with the spinal disk the inferior end plate is the bottom side of a vertebra. so the Anterior section of the inferior end plate of C# or T# would be the inside if the person side of the bottom side of the vertebra.
What is the name of the neurotransmitter that produces an end plate potential?
Acetylcholine
How does the direction of an electrical circuit move on a battery device differ from the direction of an ac current?
In a DC circuit (battery), the lower potential is always on one 'end' of the circuit so the current always flows in the same direction. In a AC circuit, a wave is generated so each end cycles between high and low potential. Current always flows towards lower potential and changes direction every time the higher/ lower potential changes
What causes an action potential when it binds the motor end plate?
Chemically gated sodium channels open up when neurotransmitters bind to receptors in the motor end plate. This causes an action potential along a muscle membrane or nerve cell.
Triggering of the muscle action potential occurs after?
Triggering of the muscle action potential occurs after acetylcholine binds to chemically-gated channels in the end plate membrane.
A folded region of the sarcolemma at the neuromuscular junction?
At the neuromuscular junction (or presynaptic end) of the sarcolemma, it is referred to as end plate synapse potential.
What happens to the muscle membrane when acetylcholine binds to receptors at the motor plate?
When acetylcholine binds to receptors at the motor plate, this binding opens ligand-gated ion channels on the motor end plate, ions diffuse through the open ligand gated ion channels, and the flow of ions causes the motor end plate to reach threshold and an action potential is generated at the motor end plate.
How do you create current from Voltage?
Electric current is what flows when the voltage is applied across a resistance. Electrons flow from the negative end to the positive end. Strictly, if everything was at the same voltage no current will flow because there is no distinction, positive or negative between the ends. So people often talk more accurately of voltage difference, or potential difference.
Motor end plate is?
Motor end plate of a cell is the dendritic portion that have cholinergic receptors to receive neurotransmitters in order to propagate an action potential.
How does the nervous stimulus pass to the motor end plate?
An activated neuron will send an action potential from upper motor neurons to lower motor neurons to effector organs. It is able to propagate the action potential to the motor end plate by release of neurotransmitters, chiefly acetylcholine. On the terminal bouton the action potential opens voltage gated calcium channels. There is an influx of calcium in the pre-synaptic cell and it pushes the vesicles that contain acetylcholine. These vesicles will pass through the synaptic cleft and bind to cholinergic receptors on the post synaptic neuron. Each vesicle has a miniature end plate potential of 0.5mV. In a normal action potential, it will depolarize the post synaptic motor neuron from -85mV to approximately 0-15mV. So that's approximately 180 vesicles.* The influx of neurotransmitters (primarily acetylcholine) will depolarize the motor end plate and propagate the action potential. *Threshold of an action potential is approximately -55mV so technically the minimum required to continue an action potential is around 60 vesicles.
Contraction mechanism in a skeletal muscle cell?
ACH is released at the end-plate potential. ACH diffuses into the sarcolemma, attaches to the receptors in the motor end plate and causes a change in the ions permeability that creates graded depolarization of the end-plate potential. Basically, it attaches to the receptors in the motor-end plate and creates the beginning process of triggering muscle contractions.
Why the current not flowing through the wire when one end is connected to the positive terminal and the other end is let open why the positive potential does not affect the electrons in the wire?
since it is not grounded ,it does not accept the flow of current
What potential motor end plate to synapse to acetylcholine synaptic cleft to special receptors on the skeletal muscle to action potential across the muscle travels down t-tubule to the what?
This is the neuromuscular junction. The action potential travels down the presynaptic motor neuron, releasing acetylcholine (ACh), which cross the synapse (neuromuscular junction), to bind to receptors on the end plate of muscle fibers, which induces depolarization, causing the muscle to contract.
