They are located top center of the engine under the cowl packs (black things inside the v)
There are six(6) spark plugs to require to change for the IS300. Not as easy to change.
The 2001 Lexus IS300 uses a 2JZ-GE inline-6 Toyota engine, and has 6 spark plugs.
http://my.is/forums/f67/is300-changing-spark-plugs-340989/
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depends on the year.. 2001 lexus is300 is 215 horsepower
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