water might, but it depends, are you talking purified normal pH water or something else? There are some enzymes whose normal function may be at very basic or acid pH, which might be denatured by neutral water. Your premise may not be accurate.
blah
yup!
yes
No
Heat and corrosive alkalis or acids
organic solvents
Yes.. There are protein and they can be denature
affected by temperature or pH cause the protein denature .
Temperature, pH, organic solvent, mechanical forces
Heat and light.
High temperature and PH value
denature