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Can I get 3rd dose hepatitis vaccine while on azithromycin antibiotic?
Wiki User
∙ 10y ago
You should wait some time after stopping azithromycin before receiving immunizations. When studied, azithromycin inhibits the ability of the immune system to build a lasting response to vaccines, probably by altering the activity of macrophages and other antigen presenting cells and the expressions of cytokines, including TNF-alpha.
See "Azithromycin Modulates Murine Immune Responses to Pneumococcal Conjugate Vaccine and Inhibits Nasal Clearance of Bacteria"
While this is a different vaccine, it's reasonable to at least extrapolate that there may be a need for caution in coadministration of azithromycin and vaccines.
Azithromycin has a long half life in the body - almost 3 days - so you should give it some time before receiving the vaccine, I'd guess 2 weeks minimum, although it depends on your dosage and how long you've been taking the medication.
Wiki User
∙ 10y ago
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