Methamphetamine, amphetamine.
Taken straight from wikipedia:
I hope this is what you needed.
Norepinephrine-dopamine reuptake inhibitor
blocking the dopamine or monoamine reuptake into the presynaptic axon ending
I believe they are stimulants.
Crystal methamphetamine acts by increasing the release of neurotransmitters like dopamine, norepinephrine, and serotonin in the brain. It binds to the dopamine transporter proteins on nerve cells, preventing the reuptake of dopamine and leading to increased levels of dopamine in the brain. This surge in dopamine results in the intense feelings of euphoria and increased energy associated with crystal methamphetamine use.
Neurotransmitters would continue to bind and rebind with the postsynaptic receptors, which would continue induction of a signal in the postsynaptic neurons, which would repropagate the initial signal. The case in drugs that block reuptake transporters (such as in serotonin reuptake inhibitor and norepinephrine reuptake inhibitor antidepressants, and dopamine reuptake inhibition found with cocaine and methylphenidate). This is also seen in cases where drugs block the breakdown of neurotransmitters at the synapse: - monoamine oxidase inhibitors (MAOIs) - Nardil, Parnate, selegiline - which prevent the breakdown of serotonin, norepinephrine, and dopamine - acetylcholinesterase inhibitors (AChE inhibitors) - organophosphase pesticides, nerve gas, racetams
Inhibits the reuptake of dopamine resulting in euphoria etc
Norepinephrine-dopamine reuptake inhibitor
blocking the dopamine or monoamine reuptake into the presynaptic axon ending
dopamine and norepinephrine
its cause your neurons to over load with electrical impulses in your brain causing your scenes to being an hallucination and causing the euphoria
I believe they are stimulants.
Cocaine is a dopamine reuptake inhibitor, causing a build-up of dopamine in the brain. That build-up is associated with the euphoric sensation often referred to as a "high."
Cocaine blocks the reuptake of dopamine and, to a lesser extent, norepinephrine and serotonin in the brain. This causes the accumulation of dopamine, leading to euphoria and excitation. The increased stimulation of dopaminergic neurons in the mesolimbic (reward) circuit leads to addiction. Alcohol binds with GABA receptors producing inhibitory effects on neural activity. This produces cognitive impairment and reduced anxiety (disinhibition). Activation of GABA receptors also produces postsynaptic dopamine release, which stimulates the mesolimbic circuit in the brain, producing euphoria and addiction.
Focalin, also known as Dexmethylphenidate, is known as a norepinephrine-dopamine reuptake inhibitor. This specific drug is not considered to be a narcotic.
Cymbalta is an antidepressant that is in the class of serotonin and norepinephrine inhibitor. Wellbutrin is also an antidepressant, but in the class of dopamine and norepinephrine reuptake inhibitors.
No. Wellbutrin (bupropion) is a norepinephrine and dopamine reuptake inhibitor, and nicotinic antagonist. It is not related chemically to opiates, and does not normally resemble them in its effects.
to understand reuptake you have to understand the basic firing of neurotransmitters: a neurotransmitter is realeased from one neuron and floats accross the synapsde or gap to activate the receiving neurons receptor site. after the other neuron has received the information from the neurotransmitter it unbinds and floats back into its original neuron and goes back into the storage tanks or vessicles. reuptake inhibtors block this process thus leaving more of the particular neurotransmitter in the synapse. different neurotrasnmitters have different effects. an SSRI or seretonin reuptake inhibitor is used for depression. cocaine is a dopamine reuptake inhibitor just like Ritalin this leaves more dopamine in the brain which causes awakefullness etc....