by nuclear membrane
Intracellular
The molecule that can bind to a receptor protein is called a ligand.
Some cell receptor is held with it some proteins that transform the signal when a particular ligand is bind. When a ligand binds to a receptor it results in conformation changes in the receptor. The receptor interact with the other protein attached to it and mediate signal transduction by producing some secondary messengers that's how the signal is amplified and create a respond.... (eg., G -Protein coupled receptor)
the lipid solubility of the ligand.
ACh binds to each ACH receptor which causes opening of ligand-regulated ion gate and the creation of end-plate potential.
Intracellular
The molecule that can bind to a receptor protein is called a ligand.
in the cell membrane depends on the receptor. A lot are in the cell membrane but some may be cytoplasmic or even nuclear depending on the solubility of the ligand and how it enters the cell.
Hormones are ligands that bond to cells and carry a specific receptor. The ligand bonds its receptor to form a complex that acquires a purpose. The ligand triggers a change in the receptor, which activates a potential biological function. Cells that do not exhibit the receptor never receive the signal.
Some cell receptor is held with it some proteins that transform the signal when a particular ligand is bind. When a ligand binds to a receptor it results in conformation changes in the receptor. The receptor interact with the other protein attached to it and mediate signal transduction by producing some secondary messengers that's how the signal is amplified and create a respond.... (eg., G -Protein coupled receptor)
receptor
yes a ligand is anything that can change the conformation of a receptor protein. hormones bind to proteins in the same way ligands do
Receptor internalization is the process by which cell surface expressed receptors are monoubiquitinated following ligand-induced activation, and subsequently taken up into the endocytic vesicles to the lysosome. The receptor will either be degraded or brought back to cell membrane were it is again able to interact with its ligands. Receptor internalization serves as a mechanism to downregulate receptor signaling upon agonistic ligand stimulation.
peni
The glycoprotein CD4 is a co-receptor. A co-receptor is "a cell surface receptor, which, when bound to its respective ligand, modulates antigen receptor binding or affects cellular activation after antigen-receptor interactions." (MediLexicon)
Neurotransmitter receptor sites on ligand-gated ion pores.
the lipid solubility of the ligand.