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No it is not!
Wiki User
∙ 11y ago
ATP inhibits hexokinase by competing with glucose for binding at the active site of the enzyme. When ATP is bound, it causes a conformational change that prevents glucose from binding and being phosphorylated. This inhibition helps regulate the glycolytic pathway by ensuring that hexokinase is only active when ATP levels are low.
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What reaction does the enzyme hexokinase catalyze?
Hexokinase catalyzes the phosphorylation of glucose to glucose-6-phosphate using ATP as a phosphate donor. This reaction is the first step in glycolysis and plays a crucial role in glucose metabolism in cells.
What are the three inhibitors of tca cycle?
1.) Increases in NADH, Succinyl CoA, ATP, Citrate inhibit citrate synthase. 2.) Increases in ATP will inhibitisocitrate dehydrogenase. 3.) Increases in succinyl CoA and NADH will inhibit succinate thiokinase.
What is the source of energy for the first step of glycoylsis?
The source of energy for the first step of glycolysis is the hydrolysis of one molecule of ATP to ADP and inorganic phosphate. This reaction is catalyzed by the enzyme hexokinase and helps to phosphorylate glucose to glucose-6-phosphate.
What is the first reaction to occur during glycolysis?
The first reaction in glycolysis is the phosphorylation of glucose to glucose-6-phosphate by the enzyme hexokinase. This step consumes one molecule of ATP to phosphorylate glucose, making it more reactive for subsequent steps in glycolysis.
What substrate is converted into glucose 6 phosphate by the enzyme hexokinase?
Glucose is the substrate that is converted into glucose 6-phosphate by the enzyme hexokinase. Hexokinase catalyzes the phosphorylation of glucose to glucose 6-phosphate in the first step of glycolysis.
Glucose to glucose 6-phosphate. Irreversible. Hexokinase/gluckokinase. Requires ATP and Mg2?
Glucose to glucose 6-phosphate. Irreversible. Hexokinase/gluckokinase. Requires ATP and Mg2+
How does cyanide inhibit mitochondrial function?
ATP decreases
Why ATP is needed not GTP for hexokinase reaction?
Atp is universal energy currency used in most reactions while GTP is used only in protein synthesis .
Name one reaction were ATP is required?
The first reaction of glycolysis, where glucose is phosphorylated (a phosphate group is added) to give glucose - 6 - phosphate requires ATP. This reaction is catalyzed by the enzyme hexokinase
What is hexokinase?
a hexokinase is an enzyme that catalyzes the phosphorylation of hexoses.
Which has a higher affinity for glucose: hexokinase or glucokinase?
Hexokinase
Which of the following is true of phosphofructokinase (PFK)?
High levels of ATP inhibit PFK
Why Hexokinase phosphorylated the glucose at first step of glycolysis?
The first step in glycolysis is catalyzed by hexokinase, an enzyme with broad specificity that catalyzes the phosphorylation of six-carbon sugars. Hexokinase phosphorylates glucose using ATP as the source of the phosphate, producing glucose-6-phosphate, a more reactive form of glucose.
Which metabolic poison can inhibit the production of ATP and therefore stop active transport?
Potassium cyanide
What proteins require ATP to function?
Proteins that carry out active transport such as Na/K ion channels requires ATP. Also metabolic enzymes such as kinases which can phosphorylate its substrate also need ATP; For example hexokinase convert the glucose to glucose 6 phosphate in the first glycolysis step with the expense of an ATP molecule.The muscle protein myosin can use ATP to flex its head, pulling on the muscle protein actin, causing the actin filament to slide past the myosin filament producing contraction of the muscle. Sometimes myosin does this with just ion transfers without requiring ATP, but the reaction using ATP is more dependable.
How is hexokinase regulated and why is it regulated?
Hexokinase is regulated by feedback inhibition of Glucose-6-Phosphate. Otherwise, you would make more glucose-6-phosphate than the cell can use at one time. you could also reduce phosphate concentrations needed for making ATP, and set up an osmotic gradient which could lead to swelling of the cells
What are the three inhibitors of tca cycle?
1.) Increases in NADH, Succinyl CoA, ATP, Citrate inhibit citrate synthase. 2.) Increases in ATP will inhibitisocitrate dehydrogenase. 3.) Increases in succinyl CoA and NADH will inhibit succinate thiokinase.
