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How does a single amino acid substitution cause hemoglobin molecules to stick together?
Wiki User
∙ 12y ago
It is when the valines link up and causes the globins to stick
Wiki User
∙ 12y ago
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How much hemoglobin can a RBC carry?
A single RBC carries 280 million hemoglobin molecules.
How does sickle cell hemoglobin differ from normal hemoglobin?
Sickle cell hemoglobin differs from normal hemoglobin primarily due to a single amino acid substitution in the hemoglobin protein chain. In sickle cell disease, a person inherits two copies of an abnormal hemoglobin gene, usually referred to as HbS. In normal hemoglobin (HbA), the amino acid glutamic acid is present at a specific position in the beta chain of the hemoglobin protein. However, in sickle cell hemoglobin (HbS), this glutamic acid is replaced by valine due to a genetic mutation. This change causes the hemoglobin molecules to stick together under certain conditions, forming long, rigid structures that distort red blood cells into a sickle or crescent shape.
Force that holds molecules of a single material together?
Cohesion
Which types of mutation causes sickle cell anemia?
No single mutation is responsible for this disease. It just happens by abnormality in the red blood cells. It affects the hemoglobin.
How does a single DNA molecule produce two identical molecules?
Two single chains bond together. The bonded chains twist together to form a double helix.
How much hemoglobin can a RBC carry?
A single RBC carries 280 million hemoglobin molecules.
How does sickle cell hemoglobin differ from normal hemoglobin?
Sickle cell hemoglobin differs from normal hemoglobin primarily due to a single amino acid substitution in the hemoglobin protein chain. In sickle cell disease, a person inherits two copies of an abnormal hemoglobin gene, usually referred to as HbS. In normal hemoglobin (HbA), the amino acid glutamic acid is present at a specific position in the beta chain of the hemoglobin protein. However, in sickle cell hemoglobin (HbS), this glutamic acid is replaced by valine due to a genetic mutation. This change causes the hemoglobin molecules to stick together under certain conditions, forming long, rigid structures that distort red blood cells into a sickle or crescent shape.
Force that holds molecules of a single material together?
Cohesion
How many heme groups are contained in one molecule of hemoglobin?
There are four hemes. So, theoretically, up to 4 oxygen molecules can bond to a single hemoglobin. However, in practice, this seldom occurs.(usually fewer)
Which types of mutation causes sickle cell anemia?
No single mutation is responsible for this disease. It just happens by abnormality in the red blood cells. It affects the hemoglobin.
How many molecules of hemoglobin in one red blood cell?
250 million X 4 = < 1 billion4- is how many o2 molecules a single HBn carries assuming they are full saturated(which they almost never are)Actually, one hemoglobin molecule can carry 4 molecules of oxygen. There are ~1 billion molecules of oxygen in each RED BLOOD CELL.
How does a single DNA molecule produce two identical molecules?
Two single chains bond together. The bonded chains twist together to form a double helix.
Difference of myoglobin and hemoglobin?
myoglobin: the molecule is compact there is no water inside it with the exception of a very small number(less than 5) of single water molecules presumably trapped at the time the molecules is folded up. hemoglobin: it iz 4 times larger than myoglobin. it is spherical molecule formed by 4 subunits which are identical in pairs . each subunits has a conformation closely resembling that of myoglobin and the aggregation is held together by extensive van der waals forces.
What are oxygen molecules?
more than one oxygen atom joined together by single covalent bonds
Why butane undergoes substitution reactions?
due to saturated and single bonded.
In which hereditary disease does abnormal hemoglobin differ from normal hemoglobin by only a single amino acid?
Sickle-cell anemia
What three terms are related disaccharides monosaccharides peptides polysaccharides?
Monosaccharides are single sugar molecules. Disaccharides are two sugar molecules joined together. Polysaccharides are saccharide polymers (chains of monosaccharides).
