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What is bioavailability?
Bioavailability is the amount of drug which reaches the site of physiological activity after administration.
How route of administration drug can control bioavailability drug?
biovability of intral nasal route
What is bioavilability in pharmacology?
Bioavailability in pharmacology refers to the fraction of a drug that reaches the systemic circulation and is available to produce an effect after administration. It is typically expressed as a percentage and takes into account how much of the administered dose is absorbed and becomes available to the body. Factors like drug formulation, route of administration, and first-pass metabolism can affect a drug's bioavailability.
What is the bioavailability of a drug?
Bioavailability of a drug is the amount of the drug that is available for use by the body after it has been metabolised by the liver.
Is there a correlation between routes of administration of drugs and drug actions?
Yes, the route of administration can significantly change the amount of drug absorbed and the potency of the drug.
Why does parental administration of a drug pose more safety risks for patients than administration by other routes?
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Why does parenteral administration of drug pose more safety risk for patients than administration by other routes?
Because after the drug has been injected it cannot be retreived..
How does chemical stability of the drugs in the gastrointestinal tact affect the bio-availability of the drugs?
Bioavailability is used to describe the fraction of an administered dose of unchanged drug that reaches the systemic circulation, so we need chemically stable drug in order to increase the chance of drug absorbance and thus increased bioavailability.
Why is a pharmaceutical equivalent not necessarily therapeutically equivalent?
They can still have different bioavailability (the amount of drug that is delivered to the site of action and the rate at whcih it is available). Pharmacetical equivalents do not have to have the same release mechanisms, and can therefore affect their bioavailability.
What is a bioequivalence?
A bioequivalent is a formulation of a drug which is equivalent to some other formulation in terms of bioavailability.
What is the difference between an injection that is given IM OR IV?
IM means Intramuscular route of drug administration, while IV means Intraveinal route of drug administration. IV route, takes the drug directly into the bloodstream resulting in 100% bioavailability instantly. Where as in IM route, drug is injected into muscle tissues, which holds the drug for a while and gradually releases into the bloodstream through the network bed of capillaries running across or surrounding the muscle tissue. In IM, the bioavailability may be slightly less than 100% of drug due to diffusion from muscle through tissue fluid and into the blood.
What is nine routes and methods of drug administration?
Intradermal, subcutaneous, intermuscular, intravenous, sublingual, otic, ophthalmic, enteral, and nasal.
