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Is T cell activation antigen specific?
Yes. The first signal that a T cell receives from an antigen presenting cell (dendritic cell) is MHC presenting an antigen (foreign peptide). This gives the T cell specificity to this antigen.
What happens when a B cell recognize an antigen?
Yes the antigen binding sites on the Cell determine the antigen which it bonds to and differentiates using histocompatabilty markers.
What occurs if a T cell binds to an antigen and the T cell does not receive a co-stimulatory signal?
The T cell enters a state of anergy. In this case, the T cell becomes tolerant to that antigen and is unable to divide or to secrete cytokines. This state of unresponsiveness to antigen is called anergy.
What does the body do when an antigen enters the body?
when a antigen enters the body then the body would send antibodies to get rid of them. The antibody doesn't get rid of the antigen they tag it by binding to it so that a cell..a white blood cell can come and destroy by phagi.
What type of cell makes blood cells?
antigen
What is a non-self antigen?
A non-self antigen is a 'Foreign' cell or chemical which is not naturally found inside the body.
Is T cell activation antigen specific?
Yes. The first signal that a T cell receives from an antigen presenting cell (dendritic cell) is MHC presenting an antigen (foreign peptide). This gives the T cell specificity to this antigen.
When MHC will be expressed?
MHC I and MHC II are always expressed. The antigen it presents on a cells surface can be foreign or it can be self. It is the T cell that determines whether what the MHC is displaying is self or not. Remember antigen can be protein, lipid, sugars, etc.
What is the difference between a antigen and a processed antigen?
An antigen can be anything from virus to bacteria to a soluble protein from outside or inside a cell. This includes both foreign and self peptides. An antibody that finds an appropriate antigen will bind to it and your B and T cells determine if it's self or not. A processed antigen came from cytosol. A protein will be taken by ubiquitin to a proteosome where it is broken up into small peptides. These peptides will make their way into the endoplasmic reticulum (through TAP) where they are exposed to MHC's.
What happens when a B cell recognize an antigen?
Yes the antigen binding sites on the Cell determine the antigen which it bonds to and differentiates using histocompatabilty markers.
Alloreactivity is a positive selection step or negative selection step?
Neither. Alloreactivity has to do with a lymphocytes reacting to a foreign antigen. Positive and negative selection are processes of central tolerance which is to say that they deal with a T cell's ability to bind self-antigen.
What occurs if a T cell binds to an antigen and the T cell does not receive a co-stimulatory signal?
The T cell enters a state of anergy. In this case, the T cell becomes tolerant to that antigen and is unable to divide or to secrete cytokines. This state of unresponsiveness to antigen is called anergy.
What do dendrictic cell do?
antigen processing and presentation
What cell is not and antigen presenting cell?
Basophils is not Phagocytic
What substances is NOT typically perceived as an antigen?
Self-antigens
What does the body do when an antigen enters the body?
when a antigen enters the body then the body would send antibodies to get rid of them. The antibody doesn't get rid of the antigen they tag it by binding to it so that a cell..a white blood cell can come and destroy by phagi.
What is an example of a self antigen?
A or B antigens of blood cells
