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The following information was taken with permission from the author (me) from the following article, A Diagnosis of Celiac Disease: What Does This Mean to Me? referenced below.
Celiac disease (CD) is neither a dominant nor a recessive genetic disorder. It is a chronic, inherited (genetic) disorder passed to the child by either the mother or the father (Celiac Disease Center, 2012). It does not require both parents to have that gene and it can occur at any time in a person's life (Celiac Disease Center). Left untreated it will lead to malnutrition (Mahadov & Green, 2011).
It is more common in females than males, with a 2-3:1 ratio (Tack, et.al., 2010), especially in individuals who test postitive for the CD gene (Lewey, 2008). The rationale for a higher female to male ratio is thought to be the higher incidence of stress and trauma to the female body (i.e. pregnancy & childbirth) (Lewey, 2008). In families that have CD, there is a 5% probability of developing the disease in first degree relatives (mother, father, child, sibling) and a 3% chance in second degree relatives (aunt, uncle, cousin, grandparent) (Celiac Disease Center, 2012). It results from an immune response (allergy) to gluten (Mahadov & Green, Tack, et.al., GIG, 2012).
Just because a person has the gene for celiac disease, does not mean they have the disorder. In fact, 35% of Americans carry the haplotypes, DQ2 or DQ8 (Celiac Disease Center, 2012), but only 1 to 1.26% of Americans have been diagnosed with CD (NIH, 2012). There are some individuals, mostly male, that test negative for the two haplotypes, DQ2 and DQ8, still have positive clinical presentations of the disease (Lewey, 2008). Usually, these individuals have had celiac disease for a long time (Lewey).
NOTE: Eating gluten does NOT trigger the gene, but rather, the gene is triggered by stress, trauma, and infections (GIG, 2012, Tack, et.al.). Examples of trauma are not what most would think, and include pregnancy, surgery, a broken bone, death in the family, etc. Some environmental factors include the amount of gluten given to the child and at what age it is given to them (Sharaf, Verna, & Green, n.d.). Infections also play a role in the development of CD (Sharaf, Verna, & Green).
Wiki User
∙ 11y ago
Wiki User
∙ 14y agoCrohn's Disease is not hereditary and is not based on dominant or recessive traits.
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Is the gene for a miniature breed of dog dominate or recessive?
recessive
How many alleles are usually in the gene pool for each trait?
Each gene has a dominate and recessive allele, so there are two types of alleles in each gene. The dominate allele is stronger than the recessive allele unless there are two recessive alleles.
What gene won't display its trait in the prescience of a dominate trait?
The recessive form of a gene, called a recessive allele, will not be expressed in the presence of the dominant form of the gene, called a dominant allele.
Why are recessive alleles not always expressed as the phenotype?
recessive alleles get masked to show the difference in a dominant gene and a recessive gene. the dominate genes masks the recessive genes to show that the dominate gene is more dominate or more likely to be the outcome than the reccessive gene but the masked gene is not always recessive.
Can celiac disease develop when a person is in their teens?
Yes, Celiac Disease can develop at anytime. For a person to develop Celiac Disease, one must carry the gene. The gene can remain "off" or it can turn "on". You can have the gene but never experience any celiac disease symptoms. Something has to trigger the gene for a person to start developing problems. My mom didn't have symptoms until she was in her 30's. Before that, she never had any problems eating grains.
What gene pair that consists of a dominate allele and a recessive allele?
the tiger of ireland
Is the gene that controls fur change in arctic foxes recessive or dominant?
It is dominate.
What form of gene that always shows even in the presence of recessive allele?
Dominate
Are alleles dominant or recessive?
Alleles are neither entirely recessive nor entirely dominate. An allele is any one of a number of alternative forms of the same gene on a chromosome.For example: say a flower only blooms either red or white flowers. There is a different allele for each color-- a red allele and a white allele. Now, one color may be dominate over the other recessive gene. For example, if the red color was dominate and the white color was recessive, then those certain alleles would be dominate and recessive, respectively. But alleles in general cannot be either recessive or dominate. It depends on the gene and it depends on the trait.
Why are traits controlled by recessive alleles on the X chromosome are more common in males than in females?
Males only have one X chromosome, so even if the gene on that chromosome is recessive there is no other gene that could dominate it. Females have two X chromosomes, so if the gene on that chromosome is recessive there is still a chance that the gene on the other chromosome could be dominate and override it.
What is a reccesive gene?
an allele that is not expressed when paired with a dominant allele. Only expressed when paired with another recessive allele.
How do you find possible phenotypes of offspring?
Mendel Diagrams. If the offspring gets a dominate gene from both parents, the offspring will exhibit traits from the dominate gene. If the offspring gets a dominate gene from one parent and a recessive gene from another, the offspring will exhibit traits from the dominate gene. If the offspring get a recessive gene from both parents, the offspring will exhibit traits from the recessive gene.
