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What does Chloramphenicol do?

Updated: 11/2/2022
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15y ago

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Chloramphenicol is a broad spectrum antibiotic. It functions by inhibiting protein synthesis in bacterial cells by binding to the ribosome. The ribosomes of prokaryotic cells are 70S where as eukaryotes have 80S ribosomes, this fundimental difference means that chloamphenicol specifcally targets bacterial protein synthesis. It is effective against Gram positive as well as Gram negative bacteria.
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Q: What does Chloramphenicol do?
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Related questions

What type of antimicrobial agent is chloramphenicol?

Chloramphenicol


What has the author Stephen Michael Kane written?

Stephen Michael Kane has written: 'The clinical pharmacokinetics of chloramphenicol and chloramphenicol succinate'


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Why chloramphenicol causes gray baby syndrome?

Chloramphenicol is metabolized by the liver. A baby's liver is not mature enough to metabolize this drug. Therefore the levels of Chloramphenicol increase in the baby's body, as there is no way for the baby to get rid of the drug. This causes cardiovascular collapse (severe hypotension), cyanosis, flaccidity, and vomiting.


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