What is a cause of a genetic disease?

Answer 1

What is a genetic disease?A genetic disease is any disease that is caused by an abnormality in an individual's genome. The abnormality can range from minuscule to major -- from a discrete mutation in a single base in the DNA of a single gene to a gross chromosome abnormality involving the addition or subtraction of an entire chromosome or set of chromosomes. Some genetic disorders are inherited from the parents, while other genetic diseases are caused by acquired changes or mutations in a preexisting gene or group of genes. Mutations occur either randomly or due to some environmental exposure. What are the different types of inheritance?There are a number of different types of genetic inheritance, including the following four modes: Single gene inheritanceSingle gene inheritance, also called Mendelian or monogenetic inheritance. This type of inheritance is caused by changes or mutations that occur in the DNA sequence of a single gene. There are more than 6,000 known single-gene disorders, which occur in about 1 out of every 200 births. These disorders are known as monogenetic disorders (disorders of a single age).

Some examples of monogenetic disorders include:

• cystic fibrosis,
• sickle cell anemia,
• Marfan syndrome,
• Huntington's disease, and
• hemochromatosis.

Answer 2

A Genetic disease is caused by an abnormality in an individual's genome. There are several types of genetic inheritance Single, Multi-factoral, Chromosome.