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NaCl = Na+ + Cl-
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A drug has pKa 5. at which PH it will be 99.9 percent ionized?
To determine at which pH a drug will be 99.9% ionized, we need to consider the Henderson-Hasselbalch equation. The pH at which a drug is 99.9% ionized can be estimated by finding the pH value that is one unit above the pKa of the drug. Therefore, in this case, the drug will be 99.9% ionized at a pH of 6.
What is free acidity?
The titratable acidity in the aqueous phase of a soil. it may be expressed in millequivalents per unit mass of soil or in other suitable units. it is the portion of total acidity that exist in the form of acid both ionized or non ionized.
Can any ionized gas be a plasma?
Yes, any ionized gas is a plasma.
What are three natural non living sources of visible light?
Anything that radiates electromagnetic waves between 390 and 700nm, i.e. Sun, Hot Metal, Ionized particles
Is celebrex a sulfa drug?
Celebrex is not a sulfa drug, it a NSAID or a non-steroidal anti-inflammatory drug. It is used to treat pain from arthritis and menstrual cramps.
Why are drugs in solid form unlikely to be absorbed in the stomach to any significant extent?
Only the lipid soluble non-ionized form of a drug can diffuse across the membrane. The pH is low in the stomach. For the acidic drugs, they are non-ionized at low pH yet they are poorly soluble. For the basic drugs, they are soluble yet ionized.
Are ionized molecules less reactive than non-ionized molecules?
yes
What is effect of pH on absorption of a drug?
the more ionized the drug is the less absorption
Why can't basic drugs be absorbed in the stomach?
The drug is mainly in its ionized form and its ionized form cannot be absorbed.
Is an ionized drug more lipophilic or less lipophilic?
An unionized drug tends to be lipophilic (and hence, would be hydrophobic). Thus, an ionized drug on the other hand would be lipophobic (i.e. the opposite of lipophilic), lipid-hating.
What happens during glomerular filtration of drugs?
The glomerulus filters are free or unbounded drugs (both ionized and non-ionized). No protein or blood cells should be able to pass through the glomeruli in normal circumstances. Only the free drug molecules are hence eliminated and the protein-bound drug molecules are returned to the systemic circulation.
A drug has pKa 5. at which PH it will be 99.9 percent ionized?
To determine at which pH a drug will be 99.9% ionized, we need to consider the Henderson-Hasselbalch equation. The pH at which a drug is 99.9% ionized can be estimated by finding the pH value that is one unit above the pKa of the drug. Therefore, in this case, the drug will be 99.9% ionized at a pH of 6.
Why do mole drug molecules have both water-soluble and oil-soluble functional groups?
The drug has to be water soluble to dissolve as gastrointestinal fluid is aqueous. The drug also has to be oil soluble as only the lipid soluble non-ionized form can readily diffuse across the lipid membrane.
Would there be any difference with an ion engine using already ionized gas instead of non ionized. ie hydrogen?
The thrust of an ionized plasma engine would be significantly greater than that of a standard oxidization engine.
How many electrons do carbon atoms have?
Carbon atoms have 6 electrons, when non-ionized
What is non biological drug biological drug?
definition of non biological
Is there a non drug cure for aids?
No, there is not a non-drug cure for AIDS.
