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Q: What is the alternative route of synthesis of acetanilide?
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Why add of little amount from acetic anhydride in synthesis of acetanilide?

Acetic anhydride and aniline are the reactants for the preparation of acetaanilide.


What is the role of the acetic anhydride in this reaction in the synthesis of acetanilide?

The chemical reaction is:C6H5NH2 + (CH3CO)2O → C6H5NHCOCH3 + CH3COOH


What is an acetanilid?

An acetanilide is an amide derived from acetic acid and aniline, once used as an analgesic and antipyretic.


What is the best route for synthesis of pyridine-4-acetaldehyde?

What is the best route for synthesis of pyridine-4-acetaldehyde?


Why is synthesis of p-nitro acetanilide carried out at low temperature?

because if the temperature rises it will give o-nitroacetanilide too.


Why can't acetanilide dissolve in HCl?

Why is not acetanilide soluble in HCL?


Most suitable for recrystallizing acetanilide?

the most suitable for recrystrallizing acetanilide is water..


Will acetanilide dissolve in hot heptane?

Yes. Heptane is an ideal recrystallization solvent for acetanilide.


How can you prepare para-nitro acetanilide from acetanilide?

used of para nitro acet anilide


Is acetanilide an amide?

yes


What is the purpose of adding sodium acetate to the reaction mixture in preparation of acetanilide?

In the synthesis of acetanilide the hydrochloride salt of aniline is used in order to increase the solubility in water. The sodium acetate acts as a base and reacts with the HCl to produce acetic acid. Once the acetanilide product is no longer a hydrochloride salt, its solubility in water is decreased and it crystalises out. The main byproducts are sodium chloride and acetic acid which remain soluble in the water and are removed when the crude product is filtered off.


What is the reaction of acetanilide with litmus?

Acetanilide is a substituted aromatic amide insoluble in water and is almost neutral so does not react with litmus.