0
What is the consequence of alternative splicing of identical mRNA transcripts?
Wiki User
∙ 11y ago
if you can chop the same mRNA transcripts in multiple ways, then a single gene may code for multiple proteins
Wiki User
∙ 11y ago
Add your answer:
Earn +20 pts
What allows more than one type of protein to be produced from one gene?
Alternative splicing greatly increases the number and variety of proteins encoded in the cell nucleus without increasing the size of the genome.
What happens during rna splicing m?
Gene splicing means cutting of gene in fragments and rejoining them according to need There are two phenomenon by which gene splicing occur one is natural i.e. post transcriptional modification and other is artifically or by chemical agent used generally in recombinant technologyPOST TRANSCRIPTIONAL MODIFICATION: Gene splicing is a post-transcriptional modification in which a single gene can code for multiple proteins. Gene Splicing is done in eukaryotes, prior to mRNA translation, by the differential inclusion or exclusion of regions of pre-mRNA. Gene splicing is an important source of protein diversity. During a typical gene splicing event, the pre-mRNA transcribed from one gene can lead to different mature mRNA molecules that generate multiple functional proteins. Thus, gene splicing enables a single gene to increase its coding capacity, allowing the synthesis of protein isoforms that are structurally and functionally distinct. Gene splicing is observed in high proportion of genes. In human cells, about 40-60% of the genes are known to exhibit alternative splicing.Gene Splicing MechanismThere are several types of common gene splicing events. These are the events that can simultaneously occur in the genes after the mRNA is formed from the transcription step of the central dogma of molecular biology.Exon Skipping: This is the most common known gene splicing mechanism in which exon(s) are included or excluded from the final gene transcript leading to extended or shortened mRNA variants. The exons are the coding regions of a gene and are responsible for producing proteins that are utilized in various cell types for a number of functions.Intron Retention: An event in which an intron is retained in the final transcript. In humans 2-5 % of the genes have been reported to retain introns. The gene splicing mechanism retains the non-coding (junk) portions of the gene and leads to a demornity in the protein structure and functionality.Alternative 3' splice site and 5' splice site: Alternative gene splicing includes joining of different 5' and 3' splice site. In this kind of gene splicing, two or more alternative 5' splice site compete for joining to two or more alternate 3' splice site.A gene-sized fragment of DNA is isolated from another organism. The bases of the fragment are spliced (joined) to the bases of the molecule by using a chemical called ligase.
When does splicing occur?
nucleus
Where to get professional Bone Marrow stromal Cell c DNA?
cDNA can be used in gene expression and cloning studies, gene mutation analysis, analysis of mRNA alternative splicing and other molecular biology fields.
Why RNA splicing important?
Because DNA cannot fit through the pores of the nuclear membrane, it is too big, the mRNA copies off the specific parts needed and sends the information to where the body needs them. Without mRNA, you could not function properly.
What is it called when molecules are cooled down?
alternative splicing
Does splicing occur in prokaryotes?
in prokaryotes only self spilicing and tRNA splicing are present there is no splicosomes are present.
Diseases that results from abnormality in alternative splicing?
cyctic fibrosis and spinal muscular atrophy(sma)
What permits a single gene to code for more than one polypeptide?
Alternative splicing permits a single gene to code for more than one polypeptide. In alternative splicing, certain exons of a gene may be included or excluded from the messenger RNA used to code for proteins.
Alternating RNA splicing?
An alternative RNA splicing is a process by which the exons of the RNA produced by the transcription of a gene are reconnected in multiple ways during RNA splicing, so as to allow production of multiple forms of protein from one gene.
Which answer best explains why the discovery of alternative splicing forced biologists to change their definition of a gene?
It showed that a gene can direct the production of more than one polypeptide or RNA.
What do you mean by splicing in electronics?
Splicing means joining in optical fibers.a process called splicing takes place to join two fibers.
What is the process called which removes introns from RNA?
RNA splicing
What allows more than one type of protein to be produced from one gene?
Alternative splicing greatly increases the number and variety of proteins encoded in the cell nucleus without increasing the size of the genome.
What happens during rna splicing m?
Gene splicing means cutting of gene in fragments and rejoining them according to need There are two phenomenon by which gene splicing occur one is natural i.e. post transcriptional modification and other is artifically or by chemical agent used generally in recombinant technologyPOST TRANSCRIPTIONAL MODIFICATION: Gene splicing is a post-transcriptional modification in which a single gene can code for multiple proteins. Gene Splicing is done in eukaryotes, prior to mRNA translation, by the differential inclusion or exclusion of regions of pre-mRNA. Gene splicing is an important source of protein diversity. During a typical gene splicing event, the pre-mRNA transcribed from one gene can lead to different mature mRNA molecules that generate multiple functional proteins. Thus, gene splicing enables a single gene to increase its coding capacity, allowing the synthesis of protein isoforms that are structurally and functionally distinct. Gene splicing is observed in high proportion of genes. In human cells, about 40-60% of the genes are known to exhibit alternative splicing.Gene Splicing MechanismThere are several types of common gene splicing events. These are the events that can simultaneously occur in the genes after the mRNA is formed from the transcription step of the central dogma of molecular biology.Exon Skipping: This is the most common known gene splicing mechanism in which exon(s) are included or excluded from the final gene transcript leading to extended or shortened mRNA variants. The exons are the coding regions of a gene and are responsible for producing proteins that are utilized in various cell types for a number of functions.Intron Retention: An event in which an intron is retained in the final transcript. In humans 2-5 % of the genes have been reported to retain introns. The gene splicing mechanism retains the non-coding (junk) portions of the gene and leads to a demornity in the protein structure and functionality.Alternative 3' splice site and 5' splice site: Alternative gene splicing includes joining of different 5' and 3' splice site. In this kind of gene splicing, two or more alternative 5' splice site compete for joining to two or more alternate 3' splice site.A gene-sized fragment of DNA is isolated from another organism. The bases of the fragment are spliced (joined) to the bases of the molecule by using a chemical called ligase.
When does splicing occur?
nucleus
Can you give me a sentence with the word splicing?
Cloning and gene splicing are are highly advanced, if not outright dangerous, practices of biology.
