0
What is the mechanism of AchE inhibitor side effects of weakness?
Wiki User
∙ 10y ago
When an acetylcholinesterase (AChE) inhibitor binds with acetylcholinesterase, regardless of whether it is reversible or irreversible, it prevents the ability of AChE to bind with acetylcholine (ACh) and break it down. Therefore, ACh accumulates in the synaptic gap, causing the postsynaptic neuron or muscle cell to fire/contract repeatedly. As this happens, a fatigue effect is reached due to depletion of chemical energy stores (ATP, etc.), and weakness results from the reduced ability of neurons/muscles to respond to further stimulation.
Wiki User
∙ 10y ago
Add your answer:
Earn +20 pts
What is the medical terminology combining form meaning ache?
algia
In the synaptic cleft of a neuromuscular junction what enzyme is always present?
Acetylcholinesterase (AchE)
Does Leonardo DiCaprio get a stomach ache from time to time?
Yes. Sometimes his stomach hurts.
What is the end product of Alcohol?
An aweful livor, dead brain cells, addiction, and a head ache.
What is the end product of alcohol digestion?
An aweful livor, dead brain cells, addiction, and a head ache.
How can a cholinesterase inhibitor improve mental function in Alzheimers disesae?
Essentially a lot of the pathways affected in AD are run by AceylCholine so a central ACHE inhibitor would allow increased ACH in the CNS and bypass the damage that may be inhibiting the synaptic transmission. This is all theoretical of course. Kevin
What is the role of acetylcholinesterase to acetylcholine?
The acetylcholinesterase (AChE) essentially works against acetylcholine (ACh). AChE will break up the ACh into its two main groups, acetate and choline so that it is not able to do its job. (In the case of certain diseases, like Alzheimer's, AChE can result in negative effects, and drugs are given to prevent the action of AChE.)
Buspar has what kind of side effects?
It's stomach ace and headache and bell ache, and ure mom
How is neostigmine chemically used to treat myasthenia gravis?
Neostigmine is a competitive irreversible inhibitor of Acetylcholinesterase (AChE), an enzyme responsible for breaking down acetylcholine (ACh). Myasthenia gravis is caused by the body producing too little ACh receptors. As stimulating the ACh receptors is needed for nervous transmission, the nerve signals cannot be transmitted causing muscle weakness and fatigue. Neostigmine is hence used to inhibit AChE so that less ACh gets broken down. This leads to more ACh binding to the ACh receptors causing muscular contraction.
A pain that rhymes with stake?
A pain that rhymes with stake would be an ache.
What are the short term effects on muscles?
Fatigue.They Ache Alot After You've Been To The Gym Or Been Working Them Too Hard! :/
What discomfort is caused from dural ectasia?
In most cases, dural ectasia occurs in the lower spine, producing low back ache, a burning feeling, or numbness or weakness in the legs.
What are the signs of being unhealthy both internally and externally?
internally: coufing,sore throat,stomach ache,and acheing bones externally: fever,rashes,weakness,flaky skin,and loss of hair
What is the plural of ache?
That is the correct spelling of "ache" (a pain, usually dull or continuous).
What is the plural for ache?
plural for ache is aches
What is a ache a noun a verb or what?
Ache is a verb.
Why does your scalp ache?
Your scalp can ache if you have had your hair pulled back tightly. It can also ache if you have a migraine headache.
