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It inhibits the action potential from reaching threshold. This is done by blocking the Na channels not allowing it to depolarize.
Depolarization occurs when a stimulus opens sodium channels which allow more sodium to go into the membrane making it less negative and more positive (toward reaching threshold). An action potential can only occur once the membrane reaches threshold which means it has reached the level needed through depolarization. An action potential is a brief reversal in polarity of the membrane making the inside more positive and the outside more negative, the reverse occurs again once the membrane reaches resting potential.
All active transportation of ions would stop and ions would be allowed to run down their concentration gradients, eventually reaching equilibrium. At this stage there would be no more electrochemical potential difference across the cell membrane.
limiting factor
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It inhibits the action potential from reaching threshold. This is done by blocking the Na channels not allowing it to depolarize.
Depolarization occurs when a stimulus opens sodium channels which allow more sodium to go into the membrane making it less negative and more positive (toward reaching threshold). An action potential can only occur once the membrane reaches threshold which means it has reached the level needed through depolarization. An action potential is a brief reversal in polarity of the membrane making the inside more positive and the outside more negative, the reverse occurs again once the membrane reaches resting potential.
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All active transportation of ions would stop and ions would be allowed to run down their concentration gradients, eventually reaching equilibrium. At this stage there would be no more electrochemical potential difference across the cell membrane.
action potential has a threshold stimulus and depolarization is just change in membrae potential where inside becomes for positive relative to outside. The AP has the ability to actually transmit info over long distance in axons once threshhold stimulus/depolarization is reached
When sodium enters the neuron, it depolarizes it. This means that the neuron becomes more positive. This can lead to the neuron reaching threshold and then initiate an action potential. When the sodium channels are NOT functional, the sodium can not enter and depolarize it. Therefore the threshold can not be met and action potential will not occur. If the sodium channels are inactive in an nociceptive neruon (carries information about pain), then the it will prevent you from feeling pain.
The factor that prevents an organism or population from reaching its full potential of distribution or activity is called the limiting factor.
Renovate to Rent - 2013 Reaching Rent Potential 1-7 was released on: USA: July 2013
You have not said what this is.
limiting factor
The destruction of ACh receptors makes skeletal muscle less responsive to nerve stimulation and more likely to prematurely fatigue. With fewer ACh receptors available to bind to ACh, the skeletal muscle cell membrane potentials have a more difficult time reaching the threshold potential and initiating contraction. Thus, the normal degree of fatigue noted during repetitive nerve stimulation is exacerbated in an individual with myasthenia gravis.
metamorphism: reaching the parent rock's threshold for either temperature and/or pressure causes a change in the rock facies.