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That isn't exactly a mutation; it's more like degradation. It would basically mean that mRNA, which is made up of multiple codons, will deteriorate into a codon, which is only 3 nucleic acids combined together. Such corrosion would probably result in the cell breaking the codon like how it normally does mRNA, or it will be absorbed into the nucleus to be combined to form a normal mRNA.

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14y ago
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13y ago

No. A stop codon in (translation) is basically part of the termination step. This causes the binding of a "release factor" that hydrolyzes the polypeptide chain and allows the transcription complex to break free, along with the polypeptide chain. Therefore, it is NOT a separate amino acid that's being added.

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12y ago

It would mean that, where the first occurence of the amino acid in the sequence should be, the protein would end, so likely to truncate the protein by a good deal and make it completely non-functional!

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11y ago

Then the mRNA molecule continues to be transcribed until a STOP codon is reached later on. This would make the protein nonfunctional

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Q: What would happen if the very last stop codon of a mRNA molecule was mutated into a regular codon?
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