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MHC I and MHC II are always expressed. The antigen it presents on a cells surface can be foreign or it can be self. It is the T cell that determines whether what the MHC is displaying is self or not. Remember antigen can be protein, lipid, sugars, etc.
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What is the function of MHC?
To bind to antigens for B and T cells to identify as self or foreign.
What does incomplete dominan ces mean?
This means that a trait which is expressed is between the dominant and recessive genes. This means both alleles are partially expressed.
A gene that is not expressed when paired with a dominant allele is called?
mutation.
Traits that typically will only be expressed in offspring if they inherit two copies of the genes for that trait is called what?
recessive traits
What type of noun is wild?
The noun 'wild' is a singular, common, abstract noun, a word for a concept. The noun 'wild' is expressed as 'the wild'.
B-lymphocytes express both MHC-1 and MHC-2?
Yes they do. MHC 1 are expressed by all nucleated calls (except neurones) and platelets. MHC 11 are expressed by B-cells, macrophages and dendtitic cells. Therefore, some cells express both types.
What cells express MHC class II molecules?
There are two classes of MHC. MHC I are expressed in all cells except red blood cells (because they lack nuclei). MHC I andMHC II are expressed in professional antigen presenting cells (APC's) that include :macrophages, dendritic cells and B cells.
Why are HLA codominantly expressed?
HLA is codominantly expressed because this gives the greatest variety and therefore the biggest chance MHC will have to bind to a peptide. MHC class 1 can bind up to 10 peptides and it is anchored 4x which makes it much more strict in terms of ability to the range it can bind compared to MHC class 2 which can bind up to 50 peptides and only anchors 2x. e.g. If you only had your mothers HLA-A, your MHC wouldn't be able to identify whatever peptides that specific HLA-A (mom's) had the ability to bind to.
What does the medical abbreviation MHC mean?
MHC = major histocompatibility complex What makes up MHC are HLA's (human leukocyte antigens), which there are subclasses for.
When was MHC Krylya Sovetov created?
MHC Krylya Sovetov was created in 2008.
Do neurons have mhc class 1 receptors?
All cells with a nuclei have MHC class 1.
Where are MHC molecules located on a cell?
MHC molecules are located in the short arm of chromosome 6.
What is MHC?
Major Histocompatibility Complex
What is the role of MHC?
MHC is to present on a cell's surface for your T cells and antibodies to determine if it is self or foreign.
Why is it an Advantage to the population of species to have a highly polymorphic MHC region?
The advantage of having a highly polymorphic MHC is that it adds to variety of which it can bind to a peptide. If MHC cannot bind to a viral or bacterial peptide then your body cannot use its' adaptive immunity to fight off an infection. The T cell requires MHC to activate and if MHC is not binding to anything because it has such a small repertoire of alleles to create a MHC molecule, it will render T cells useless. So to have a highly polymorphic MHC gene that can encode to bind to many different peptides is advantageous for survival.
Is MHC class 1 the same as HLA class 1?
The answer previously here about MHC referring to mice and HLA referring to humans is catagorically untrue! HLA and MHC are in fact the same, so HLA class 1 = MHC class 1. Same goes for class 2.
MHC antigens are?
Peptides
