Blood type AB has both A and B antigens.
On the surface of red blood cells Take A type blood, for instance. It has antigens against B type blood contact on its cell surface.
Type A and B red blood cells differ in the antigens they express on the cell surface. The still carry out the same tasks (transportation). The antigens on the surface of these cells are what is recognised by the immune system - so that it knows the cell is part of the body and not foreign.
The blood antigens A, B, and Rh are located on the membrane of the red blood cell. These antigens are hereditary.
Blood types are defined by cell surface markers called antigens. For example, if you have the "A" antigen then you have type A blood. The antigens act as a backstage pass in your body giving it permission to be there. If you introduce a blood type that has different antigens than those occurring naturally on your blood cells, then those different antigens will be perceived as "foreign" by your immune system. That means that your immune system will treat the different blood type like it would an infection. Antibodies will bind to the foreign antigens causing them to clump (agglutinate) which can clog or block smaller blood vessels. This is especially dangerous in the kidney and can lead to renal failure and possibly death.
Rh factor
The essentials of Type O negative blood:Type O: there are NO ABO antigens on the cell surface; therefore O = zero.Rh negative: there are NO Rh antigens on the cell surface; therefore negative = zeroIt is known as the Univeral Donor as it can be given as an emergency blood tranfusionBabies of an Oneg mother might be jaundiced (high bilirubin) after delivery
Antigens work as bar-codes to help the immune system differentiate between body cells and pathogens. Normally the body will not attack its own cells, but is programmed to attack those with foreign antigens.
Everyone's blood cells have the same cell architecture and functional components (all blood cells are biconcave disks and contain hemoglobin unless there is a genetic disorder). However, the blood types are the result of different antigens (proteins, carbohydrates, glycoproteins, or glycolipids) on the surface of the blood cells. The most frequently seen A, B, AB and O blood system is caused by different carbohydrate antigens. People with type A have type A antigen, people with type B have type B antigen, people with type AB have both antigens, and people with type O have no antigens. These antigens facilitate rejection of blood by activating the immune system. It turns out that the immune system in a person whose blood does not have the antigen type in the transfusion blood recognizes the transfusion blood as foreign. This elicits an immune response to eliminate the 'invaders' and can result in the clumping of transfused blood cells due to antibody binding, causing the clogging of smaller vessels. Other blood type systems such as the Rhesus system involve other groups antigens on blood cell surfaces.
All cells produce antigens, or cell surface markers. The only question is whether the antigens are self antigens which means they belong in the body or they're foreign antigens which means they are an invading bacteria or virus (or a cancerous cell).
erythrocytes source: medical language 2nd ed. susan turley
I think its Rh factors.
Antigens- Each human being has his or her own unique cell surface antigens, as do to all other living things, including bacteria, virus, animals, and plants.