A b-12 deficiency.
Intrinsic factor or gastric intrinsic factor is a protein produced by the stomach. It is used to absorb vitamin B12 in the small intestine. When there is a deficiency of the Intrinsic factor, there is a deficiency in the absorption of B12 into the body and this leads to pernicious anemia.
Intrinsic Factor. This, also known as gastric intrinsic factor (GIF),isa glycoprotein produced by thestomach necessary for the absorption ofB12 there and in the small intestine.
Gastric juice is produced in the stomach. Gastric juice is produced in the Gastric glands.
Gastric acid is part of the "juices" produced by the stomach.
the gastric canal has an important clinical role in the stomach as it allows for gastic juices to be removed before absorption
HCl (about 0.1M) is produced your gastric cavity (stomach).
Ghrelin is produced in the stomach and small intestine.
Gastric acid my dear =) lol
No, hydrochloric acid (HCl) is not necessary to produce the intrinsic factor for cobalamin. HCl is needed along with gastric enzymes to free Cobalamin (B12) from its polypeptide linkages in food. The intrinsic factor involved with the digestion and absorption of Cobalamin (B12) is a glycoprotein.
alhlorhydria
Clinical trials are underway and mostly concentrate upon optimizing treatment of gastric MALT lymphomas that involve H. pylori.
PA is caused by a deficiency of Intrinsic Factor (IF). IF is a required factor in Vitamin B12 absorption through the gastrointestinal tract. IF deficiency is diagnosed by Schilling's test, as well as Gastric IF analysis and clinical rpesentation (macrocytic megaloblastic anemia, often showing hypersegmented neutrophils, along with normal Folic acid levels).