0
Why do some mutations not affect the amino acid sequnce of a protein?
Wiki User
∙ 8y ago
When the nucleotide in 3rd position of codon is change it does not change the aminoacid and is called point or silent mutation.
Wiki User
∙ 14y ago
Wiki User
∙ 12y agotriste
Add your answer:
Earn +20 pts
Can you Describe how the amino acids changes in the protein affect the function of the protein and how this causes disease?
Can you describe how the amino acid changes in the protein affects the function of the protein?
Does amino acids affect protein functions?
The sequence of amino acids affects protein function. The three-dimensional structure of a protein determines its function. The three-dimensional structure of a protein is determined by the sequence of its amino acids.
Which of these statements represents a common misconception regarding point mutations?
mutations increase variety in a population. (apex)
Why does mrna mutation affect the amino acid sequence?
The codon UGU codes for the amino acid Cysteine. The codon UGG codes for the amino acid Tryptophan. Therefore the mutation will cause the amino acid Cysteine to be replaced with Tryptophan. These amino acids are quite different, and the final shape of the protein could be changed as a result. This could affect the function of the protein.
How might a point mutation in a gene affect the reasulting protein?
point mutations include substitutions insertions and deletions of a single nuceotide in DNA. CONSIDER: insertions and deletions have a greater effect on proteins that do substiutions because insertions and deletions affect every amino acid that is specified by the nucleotides that follow the point of mutation CONSIDER: a substitution affects a single amino acid a change in more than one amino acid is more likely to alter the ability of the protein to function narmally than is a change in a single amino acid CONSIDER: follow me on twitter @Rocco_Gone_Ham
Why does an insert mutation usually cause more defects during protein synthesis than a point mutation?
Insertion mutations can affect many amino acids in the protein.An insertion mutation usually causes more defects during protein synthesis than point mutation because an insertion mutation will affect many amino acids in the protein.
Why can some gene mutatuions be harmful while others have no effect?
Let's consider a simple example: protein-coding genes. Mutations, or changes in the DNA sequence of the gene, can alter the amino acid sequence of the protein it codes for, if the new sequence translates into different amino acids. Because the genetic code is degenerate, some amino acids are specified by multiple codons, so some mutations may not alter the amino acid sequence at all. Such mutations, called synonymousmutations, have no affect on the protein. Mutations that alter the amino-acid sequence of the protein, called non-synonymousmutations, may or may not have an affect. Most proteins can tolerate some changes to that sequence and not be significantly affected, but if the sequence change is large enough, or occurs at a critical point so that the structure of the protein is significantly altered, then the protein may become non-functional. If that protein is essential to an organism, such a mutation may be lethal.
Why does the order of amino acid acids affect the structure of a protein?
The order of amino acids can affect the protein's shape.
Why does an insertion mutation usually cause defects during protein synthesis than a point mutation?
Insertion mutations can affect many amino acids in the protein.An insertion mutation usually causes more defects during protein synthesis than point mutation because an insertion mutation will affect many amino acids in the protein.
Why does an insertion mutation usually cause more defects in protein synthesis than a point mutation?
Insertion mutations can affect many amino acids in the protein.An insertion mutation usually causes more defects during protein synthesis than point mutation because an insertion mutation will affect many amino acids in the protein.
Can you Describe how the amino acids changes in the protein affect the function of the protein and how this causes disease?
Can you describe how the amino acid changes in the protein affects the function of the protein?
How many point mutations would have to occur for an incorrect amino acid to be placed into the protein?
Minimum one (1)
Does amino acids affect protein functions?
The sequence of amino acids affects protein function. The three-dimensional structure of a protein determines its function. The three-dimensional structure of a protein is determined by the sequence of its amino acids.
Why do some mutations have no effect?
Some mutations have no or little effect due to the redundancy of the DNA code.DNA consists of pairs of codons, which are made up of 4 different types of nitrogenous bases. Therefore, DNA is able provide enough unique codes for 4x4x4=64 different amino acids. However, only 20 types of amino acids exist, which indicates that 19/20 of those amino acids have at least more than 1 codon to encode it.For example; If the codon ACU mutated to ACC, how that that affect the protein?Well, it would not effect the protein at all, because both ACU and ACC encode the amino acid threonine.In addition, some amino acids have very similar properties to other amino acids. Even if amino acid X was replaced with amino acid Y, the effect on the protein may be small or non-existing if X and Y share similar properties.
How do mutations affect translations?
A frameshift mutation may cause a change in the codon sequence, specifically the 3-base sequence which is responsible for coding a specific amino acid. A different protein, a non-functional one, or no protein at all may be the result of this change.
Why does the the order of amino acid affect the structure of a protein?
The order of amino acids can affect the protein's shape.
Why can missenes mutations not have an effect on protein function?
Say the part of the gene that is mutated does not change the amino acid sequence of the protein made through the mRNA; hydrophobic amino acid stays hydrophobic. We have many of these small nucleotide polymorphisms in our genomes and they are useful trackers of human migrations, for instance.
