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The synthesis occurs in acid conditions which protonate the amino group, the NaHCO3 lowers the pH so that the amino group is no longer protonated.

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Q: Why do you use NaHCO3 in the synthesis of benzocaine?
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Why is solid nahco3 used instead of aqueous nahco3 in the synthesis of tert-butyl chloride?

The solid is used so that no water is added to the reaction, as water would stop the reaction.


Is benzocaine an amide based anesthetic?

No, benzocaine is an ester.


Can you smoke benzocaine?

It is not safe or recommended to smoke benzocaine. Benzocaine is a local anesthetic that can cause serious health risks if smoked, such as lung irritation, respiratory issues, and potential overdose. It is important to always use medications as directed by a healthcare professional.


Why the amino group of p-aminobenzoic acid does not participate in the synthesis of benzocaine?

Its because its an aniline and that is less electrophilic than an alkyl amine thats also there so that will be used instead.


Does benzocaine expire?

Yes, so make sure you use it whenever you have pain.


What is a benzocaine?

A benzocaine is a local anaesthetic used as a topical pain reliever.


What is the difference between benzocaine and benzocaine hydrochloride?

benzocaine hydrochloride readily dissolves in water and bezocaine is only very slightly soluable in cold water


Can you get arrested if you have benzocaine?

if the police want to use it as conspiracy to supply? depends on how much benzo


Most common use for NaHCO3?

sodium bicarbonate


What is the reaction for synthesis of benzocaine?

I believe a chloride salt of the benzocaine is the product as the HCl acid attacks the amine functional group. however ethanol may also be formed from the hydrolysis of the ester and create a carboxyl group attached to the benzene ring. This will leave two products at the end of the reaction. I myself need some clarification on the resulting products whether it be a mixture of 2 products or one product.


Where can you buy Benzocaine?

For 99.9% Benzocaine from £140/kg plus delivery, email - sales@timchem.co.uk


Why use NaHCO3 in a photosynthometer?

source of CO2 source of CO2