Want this question answered?
the principle of tablet compression machine is based on hydrollic principle
The AWC works in tablet compression machine based on the hydraulic principle.
compression and tension are opposite. compression pushes the crust together but tension pulls it apart
20 to 30 C.
by using the dry compression method for tablets to avoid the moisture present in the tablets
disks
In the tablet compression machine main principle is compressing the upper & lower puch in a die hole . the hydraulic pressure plays a key role if we increase the hydra. pressue more compressing force on tablet then it becomes more hard.
Bioavailability is the amount of drug which reaches the site of physiological activity after administration.
what is the tblet hardness,what is its unit ,we aply hydraulic pressure on tablet compression mchine but in result we gain hardness on tablet,how the pressure is converted into hardness unit. Friability refers to the ability of the compressed tablet to avoid fracture and breaking apart during transport.
relationship between the first pass effect and bioavailability
Bioavailability of a drug is the amount of the drug that is available for use by the body after it has been metabolised by the liver.
Bioavailability refers to the amount of a vitamin that is absorbed and used by the body. When a folate supplement is taken on an empty stomach, the bioavailability is 100 percent.