Because the States (Reigns, Duchies, Republics etc.) had been not able to effectively oppose to the foreign powers (France, Spain, Holy Roman Empire), which were attempting to conquer the country.
France
The Dutch took control of the spice trade from the Portugese in the fifteenth century.
France
Fascism was invented in the late 19th century, but it was founded in France. The idea only arrived in Italy or Spain in the early 20th century and only had strong political influence in the 1920s (in Italy) and the 1930s (in Spain).
Rome.
Trade in early Rome was not limited to the area of Italy. Archaeological finds have shown that the Romans and the Latins imported ceramics from the Greeks of the mainland as well as from the Greeks of the Italian colonies (settlements) and from the Phoenicians as early as the late 8th century BC/early 7th century BC.
during the late 11th century and early 12th century.
Samuel de Champlain during the early part of the 17th century
it became popular during the 16th century.
Thomas Edison
Futurism started in Italy in the early 20th century.
The Renaissance is believed to have begun in Italy during the 14th century. The English Renaissance began in the early 16th century, and continued until the early 17th century, focusing more on literature and music than visual arts. It is most characterized by famous writers such as John Milton, William Shakespeare, and Francis Bacon.