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no DNA synthesis occurs in 5'-3' as well as in 3'-5' direction. only the difference is that ,that it is continuous in 5'-3' direction but discontinous in 3'-5' direction. this is because enzyme DNA polymerase III can synthesize DNA contionously in 5'-3' direction only.

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No DNA synthesis always occus in the 5' to 3' direction as there is no DNA polymerase that work in the other direction as it is too thermodynamically unfavourable. The cells solve the problem of having to synthesize in a 3' to 5' direction by synthesizing in reverse in discontinuous pieces. Technically there's never any direct 3' to 5' synthesis.

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DNA polymerase can add nucleotide to 3' end of primer or growing strand of DNA so in one direction it remains continuous ie leading strand while in in other strand it starts little later when it get enough space to grow in opposite direction then after synthesizing short strand it again goes to newly unwind strand and repeats the process, but the growth remains in 5' to 3' direction moving on template from 3' to 5' direction.

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12y ago
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1mo ago

DNA polymerase can only add new nucleotides to the 3' end of the growing DNA strand. This is because the nucleotides being added have a 3' hydroxyl group that participates in a phosphodiester bond with the 5' phosphate group of the previous nucleotide. This polarized structure dictates the directionality in DNA replication.

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15y ago

DNA polymerase can only add to the free 3' end as it contains the OH group needed for binding.

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Q: A new DNA strand elongates only in the 5' to 3' direction because?
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Why transcription is unidirectional?

Transcription is unidirectional because RNA polymerase can only read the DNA template strand in one direction (3' to 5') to synthesize the complementary RNA strand in the 5' to 3' direction. This allows for the accurate and efficient synthesis of RNA molecules from DNA templates.


Why is replication on one strand of DNA continuous while on the other strand the replication must be discontinuous?

DNA replication proceeds in opposite directions on the two strands of DNA due to their antiparallel structure. The leading strand is synthesized continuously towards the replication fork, while the lagging strand is synthesized discontinuously in segments called Okazaki fragments away from the replication fork. This difference is due to the need for primers to start each new DNA fragment on the lagging strand.


What is the direction of synthesis of the new strand?

DNA replication proceeds in the 5' to 3' direction, meaning that the new DNA strand is synthesized by adding nucleotides to the 3' end of the growing chain. This is due to the antiparallel nature of DNA, where one strand runs in the 5' to 3' direction and the other runs in the opposite direction.


Which of the following statements best explains why the leading and lagging strands are synthesized using two different mechanisms?

The leading and lagging strands are synthesized using different mechanisms because DNA replication occurs in a 5' to 3' direction, but the two strands of DNA are antiparallel. This means that one strand is oriented in the 3' to 5' direction (leading) and the other in the 5' to 3' direction (lagging), requiring discontinuous replication on the lagging strand.


Why is the leading strand considered continuous?

The leading strand is considered continuous during DNA replication because DNA polymerase synthesizes the new strand in the 5' to 3' direction continuously in the same direction as the replication fork is moving. This allows for the newly synthesized strand to be made in one continuous piece.

Related questions

Why transcription is unidirectional?

Transcription is unidirectional because RNA polymerase can only read the DNA template strand in one direction (3' to 5') to synthesize the complementary RNA strand in the 5' to 3' direction. This allows for the accurate and efficient synthesis of RNA molecules from DNA templates.


Why is replication on one strand of DNA continuous while on the other strand the replication must be discontinuous?

DNA replication proceeds in opposite directions on the two strands of DNA due to their antiparallel structure. The leading strand is synthesized continuously towards the replication fork, while the lagging strand is synthesized discontinuously in segments called Okazaki fragments away from the replication fork. This difference is due to the need for primers to start each new DNA fragment on the lagging strand.


What is the direction of synthesis of the new strand?

DNA replication proceeds in the 5' to 3' direction, meaning that the new DNA strand is synthesized by adding nucleotides to the 3' end of the growing chain. This is due to the antiparallel nature of DNA, where one strand runs in the 5' to 3' direction and the other runs in the opposite direction.


Which of the following statements best explains why the leading and lagging strands are synthesized using two different mechanisms?

The leading and lagging strands are synthesized using different mechanisms because DNA replication occurs in a 5' to 3' direction, but the two strands of DNA are antiparallel. This means that one strand is oriented in the 3' to 5' direction (leading) and the other in the 5' to 3' direction (lagging), requiring discontinuous replication on the lagging strand.


Why is the leading strand considered continuous?

The leading strand is considered continuous during DNA replication because DNA polymerase synthesizes the new strand in the 5' to 3' direction continuously in the same direction as the replication fork is moving. This allows for the newly synthesized strand to be made in one continuous piece.


In what direction can a DNA polymerase work when catalyzing the addition of nucleotide monomers to build a strand of DNA?

A DNA polymerase can only add nucleotide monomers to the 3' end of a growing DNA strand, meaning it works in a 5' to 3' direction. This is because the enzyme can only add nucleotides to the hydroxyl group on the 3' carbon of the sugar molecule.


The continually elongating strand of new dna at one side of a replication fork during dna replication is known as?

The continually elongating strand of new DNA at one side of a replication fork during DNA replication is called the leading strand. It is synthesized continuously in the 5' to 3' direction by DNA polymerase.


Describe the significance of Okazaki fragments?

Okazaki fragments are created during DNA replication because DNA Polymerase can only add nucleotides in a 5' to 3' direction. This means that one strand (the leading strand) can be continuously created, but the other strand (the lagging strand) runs in the opposite direction. This means that loops must be created and shorter parts of DNA replicated one at a time. This creates fragments on the lagging strand. The RNA primers on this strand are later replaced with DNA by DNA Polymerase I, and joined together with DNA ligase.


At each replication fork one new strand of DNA is made of many small pieces. what is the strand of DNA called?

The strand of DNA made of many small pieces at each replication fork is called the lagging strand. These small pieces are known as Okazaki fragments and are later joined together by DNA ligase to form a continuous strand.


Why can't DNA polymerase synthesize a new strand of DNA without the help of a RNA primer?

Because DNA Polymerase requires the OH on the 3' as an active site. It uses the OH on the 3' end of a nucleotide to attach a phosphate from the 5' end of the next nucleotide. It only works in this direction, and that is why DNA polymerase works 5' to 3'.


Why is the lagging strand replicated with stretches of Okazaki fragments and that is why its synthesis is considered to be?

The lagging strand is replicated discontinuously because DNA synthesis can only occur in one direction, so it is synthesized in short stretches called Okazaki fragments. This helps to ensure that both strands are replicated accurately and efficiently.


During DNA replication a primer attaches to a template strand of DNA and begins a new strand. After the primer has attached an enzyme extends the new strand of DNA by adding nucleotides that correspon?

The enzyme responsible for extending the new DNA strand by adding nucleotides is DNA polymerase. It reads the template strand and adds complementary nucleotides to form a new DNA strand. DNA polymerase can only add nucleotides in the 5' to 3' direction.