Because in the pH changes the shape of the active site because they will it changes the shape on the enzymes active site therefore the substrate can not fit anymore.for better explanation look at this website:http://www.phschool.com/science/biology_place/labbench/lab2/ph.html
Changing the pH either gives H+ ions or OH- ions to the given solution. This in turn reflects in the net charge of the protins (Zwitterionic!) present in the solution. For example: increasing the pH above a particular pI makes a protein negatively charged and vice versa.
If the pH level is too high than enzyme's active sites will be denatured. This makes it impossible for the enzyme to fit with the substrate.
Esssentially increasing the pH decreases the rate of enzyme activity.
A change in the pH may cause the enzymes not to be well funtioning when breaking the food molecules down . If th pH is changed to an extremely high rate , the pancreas would release less enzymes and this would cause constipation , Diseases of lacks of several nutrients that are not able to be converted too soluble molecules and a problem in the digestive system which may turn out to be a severe case ,
Enzymes work within an optimal range of pH levels. If the ph level is either above or below the range, it could denature and kill the enzyme.
actors such as temperature and pH can affect an enzyme's rate of reaction because enzymes are sensitive to pH and heat. Most enzymes can only function in a particular temperature or pH range, and as the enzyme works out of its normal temperature and pH range, it will denature (change in shape so that the active site no longer fits with the substrate and the enzyme can't function).
Temperature, pH, solute concentration, and salt content just to name a few. Temperature and Ph affect the function of enzymes because our body has a temperature of around 37 degrees and the conditions in our stomach are acidic. So9f or the enzyme to work properly then the working condidtions have to be at least 37 degrees and they need to acidic otherwise the enzyme won't work properly.
This serves two functions; first, it stops the enzyme-catalyzed reaction by changing the pH to one unsuitable for the enzyme (the enzyme is denatured at high pH and so unable to function). Second, it deprotonates the p-nitrophenol to give the yellow colored p-nitrophenylate.
A very low pH can break the hydrogen bonds in an enzyme which causes the shape of the enzyme to change shape making the enzyme unable to do it's job. This is called "denaturation" However some enzymes such as pepsin only work in a low pH (pepsin works best in a pH of about 3) so it does depend on the enzyme.
they're dependent on color and taste
The activity of an enzyme is affected by temperature, pH and the concentration of the substrate.
It will affect the shape and lead to reduced activity.
Changing the pH in the environment that an enzyme works in can change how active it will be. Most will be active in a narrow range. Pepsin, a stomach enzyme, will only work at very acid pHs and will become inactive at higher pH than 2.
Enzymes function optimally at a patricular temperature and pH. If the temperature is decreased or increased, the enzyme will not function as effectively. The enzyme is most active only at a patricular temperature and pH. Hence, these two factors are very important for enzyme action.
actors such as temperature and pH can affect an enzyme's rate of reaction because enzymes are sensitive to pH and heat. Most enzymes can only function in a particular temperature or pH range, and as the enzyme works out of its normal temperature and pH range, it will denature (change in shape so that the active site no longer fits with the substrate and the enzyme can't function).
Temperature, pH, solute concentration, and salt content just to name a few. Temperature and Ph affect the function of enzymes because our body has a temperature of around 37 degrees and the conditions in our stomach are acidic. So9f or the enzyme to work properly then the working condidtions have to be at least 37 degrees and they need to acidic otherwise the enzyme won't work properly.
Simply put, enzymes are proteins and proteins can denature (break) under the right conditions. These conditions would include temperature and pH (however these are not the only factors) and so the changing of pH could definitely affect hexolkinase (or did you mean hexokinase? which would make more sense).
Ph level, enzyme concentration, substrate concentration etc
pH and Temperature both impact the enzyme's function.
yeh it can
If you change the pH, the enzyme can become inactive and won't be able anymore to forfill its function.
Pepsin