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Fructose is mainly metabolized in the liver. The first step in its metabolism is conversion to fructose-1-P by fructokinase. Fructose-1-P can activate a signaling pathway that leads to activation of a protein called JNK. This protein phosphorylates another protein, IRS-1 at a serine residue, inhibiting it. Since insulin signaling requires IRS-1 to work properly, congratulations! Your liver is now insulin resistant. As a result, your pancreas works harder to make up for it, producing more and more insulin. This is fructose induced hyperinsulinemia. Eventually, your pancreas won't be able to keep up and you will achieve Type 2 Diabetes Mellitus.
What else can I help you with?
What are the problems of insulin?
Hyperinsulinemia
Is high triglyceride level is associated with hyperinsulinemia?
yes
Which laboratory result is associated with hyperinsulinemia in children?
Triglycerides
What molecule is fructose?
no fructose is not a molecule
The secretion of the seminal vesicles is rich in the monosaccharide called?
It is rich in fructose.
When you add Fructose and fructose does it gives you glucose?
No. Fructose and glucose are two different, simple sugars or monosaccharides. Fructose is a ketohexose. Glucose is an aldohexose.
Which is the sweetest natural sugar?
Fructose
Which is the bigger carbohydrate sucrose or fructose?
Fructose
Is lipid found in fructose?
No. Fructose is a carbohydrate.
Is fructose soluble?
Fructose is soluble in water.
Name the sugar which is found in fruit?
Fruitcose and Glucose [fructose, might be the same as fruitcose]
What are the other isomers of fructose?
The other isomers of fructose include D-fructose, L-fructose, and D,L-fructose. These isomers differ in the arrangement of functional groups around the asymmetric carbon atoms, leading to different spatial structures. Fructose typically refers to the D-fructose isomer, which is the most common form found in nature.
