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The newly formed (nascent) protein [amino acid] chain - as it exits the Ribosome Protein Bio-Assembly Miracle - is directed to either the exterior of the endoplasmic reticulum - also known as The Cytoplasm - or to the interior of the endoplasmic reticulum.

As it is extensively known that there are several types of {cytoplasmically periferal} ER, there are sequences of the nascent protein chain, called leader sequences, that direct the nascent proteins to their Cytoplasmic ER destination, - where either the leader sequence will be removed and the remaining protein segment activated, or a portion only of it is removed and the location process continues as above until the protein reaches it's Bio-desired active location.

When the protein reaches its destination its processing is completed and it is folded into its natural three dimensional conformation.

Further Aggregation may and often does occur.

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12y ago

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