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Fentanyl
Fentanyl is an odorless,rapid-acting opioid,it can alleviate pain without causing any loss of consciousness. It is powerful,nearly 80 times more than morphine.
503 Questions
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Will Fentanyl show up in a blood test?
If it is specifically tested for, then Fentanyl will show up on a lab test. But they have to request for your urine to be tested for Fentanyl. On any 9 panel or 12 panel, no it doesn't show up.
Can you take co-codamol with Fentanyl patches?
You probably won't notice it (the Schedule IV version of codeine, what most people get, is pretty weak compared to Fentanyl) but it and similar lower-end opiates are used for breakthrough meds with Fentanyl patches.
Is Fentanyl more potent than morphine?
Yes - as a synthesized opiate, Fentanyl is the strongest opiate available, and is 100x stronger than morphine.
Which is the best Fentanyl patch?
The best is still the original - Duragesic (brand name) made by Janssen Pharmaceuticals
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What is the best part of the body to apply a Fentanyl patch?
It depends on the patient - by instruction, the patch must be applied on the upper torso or upper extremities (arms). Most people tend to put them on their back or chest, but I learned early on that for the back you need someone to change them, and the chest/stomach area has both too much hair and the skin flexes too much with activity.
As a result, for many years I've worn them on my biceps - they're flat, the patches easy to put on them with one hand, and the skin doesn't flex very much there. When using 1 100mcg patch, I just switch arms when it's time to put a new one on. When I have to increase to 2 100mcg patches, I use both arms, but take one off a few hours before the other to clean it and let the skin breathe before putting on a new one and taking the other one off. That way your dosage doesn't drop much during the process, and if you feel breakthrough you can take a Percocet or whatever your breakthrough med is to cover it.
The key to keeping a patch on (see the link to my answer on that below) is to make sure the skin is clean and there's no hair present. The literature says not to use any Isopropyl alcohol - that's because it leaves a residue. Problem is, it's difficult to remove skin oil and dirt without it. To get around the problem, clean it with Iso, then rinse the area well to make sure any residue is washed off. Dry the skin well, then apply the patch. If there's a lot of hair or micro-hairs, you might need to shave it off as well. Before you put the patch on, hold it between your hands (still attached to the backing) for about a minute to soften the adhesive. Apply it, then put your hand over it for another minute to ensure the adhesive gets a good bond to the skin. You'll find it sticks pretty well after that.
How strong is the 50mcg Fentanyl patch?
strong enought that if your arent opiate tolerant that the lowest dose of the patch will make you overdose, dont be stupid, when it says for opiate tollerent patients only it really facking means it.
Is a Fentanyl 100 mcg patch and a duragesic 100mcg patch the same dosage?
No - they are 2 completely separate drugs. OxyContin is the time release version of Oxycodone, and typically lasts from 7-12 hours.
Duragesic / Fentanyl transdermal patches are timed release fentanyl over a 48-72 hour period. Its release is regulated by body heat. It is a much more reliable and steadier drug than OxyContin, in that it doesn't wear off as fast, and it lasts a lot longer.
The precursor used is N-Phenethyl-Piperidone (NPP) which can be easily synthesized from Piperidone and Phenethyl-tosylate or Phenethyl-bromide through a simple SN2 mechanism.The NPP is reacting with Aniline giving the Imine derivative which is reduced to the 4-Anilino-N-Phenethyl-Piperidine (4-ANPP). The 4-ANPP is then reacted with Propionyl Chloride giving Fentanyl which is then purified.
Does Fentanyl cause pinpoint pupils?
Yes it does. But not to the extent that stronger opioids do. It is much weaker than oxycodone, morphine etc. Constriction of pupils is most common when somebody overdoses on tramadol.
Is hydrocodone in Fentanyl patches?
It's extremely common for Duragesic patients to have Hydrocodone, Oxycodone, or other acute opiate meds (Demerol, Methadone, etc.) as their breakthrough medication. Remember that patches are for primary, chronic pain; increased activity can cause the pain to increase past the point of patch effectiveness, which is termed "breakthrough pain". In those cases, an acute (short term) pain med like Vicodin or Percocet is used to deal with the short term increase.
I myself have used Percocet 10/325's for about 10 years in conjunction with my patches, about 120/month. At some point though, if breakthrough becomes constant, then it's time to re-evaluate the need for a higher dose patch or patch combination. I've had to deal with this several times over the years, and I prefer to use pills because it gives you more spot control of the pain. But for severe increases (see my bio for more), adding another patch is really the only way to go.
What does a Fentanyl pill look like?
the Fentanyl Buccal Tablets I take for cancer pain are small, round, white tabs with 1, 2, 3, 4, 6, or 8 on them refering to the hundreds of mgs.
Can you mix Fentanyl and Wellbutrin?
Most opiate patients are chronic pain patients in formal Pain Management programs, and since Depression is common to all pain patients, PM programs typically require patients to go through some type of mental health therapy. Taking Wellbutrin and other AD's with Fentanyl and other opiates is common, but of course not everyone is the same. For some like me, AD's have the opposite effect, so I can't take them. There are those that do benefit though - the best course is to try it for a short period to see if you're getting any benefit.
I was wondering why someone would cut open a Fentanyl patch and rub the gel on their gums?
to get high if you cut it open and lick it or rub it on your mouth its absorbed right away the patch is time release through the patch eight to twelve hrs so if some one is doing this its probably to get high
What is the street value for Fentanyl transdermal system 50 mcg?
$17.00 to $20.00 give or take i guess idk for sure though so dont quote me.
Any fentanyl transdermal system patch is worth whatever the mcg is and sometimes a little more. So say a 25 mcg patch would be between $25 to $30 or say a 50 mcg patch would get between $50 and $60.
What is stronger than Fentanyl?
I believeOxymorphone would be the closest Legal Opioid in Strength; if used in combination with oxycodone (which metabolizes into oxymorphone) Oxymorphone can reach 200 times the potency in relation to Morphine (although due to its lack of metabolitic absorption in it's current legal form, you would have to have to use it in it's IV/IM form plus oxycodone as a metabolic primer in order to reach the full potency of oxymorphone). It sounds like a lot of experimentation and work so if you are using fentanyl be cautious because it is a 100 times stronger than morphine without experimenting with mixtures. Although Methadone is about 10 times the potency of morphine the half-life (length of metabolism in the body) makes it another dangerous narcotic. I hope I shed some light on your question, and I hope you are not taking a combo of the above drugs mentioned. Also opioid dependency is a life long battle, and if curiosity for the sake of knowing is the only purpose that's OK but if you are fighting the painful fight there is help and people who care and know what its like ; ) .
How do you take Fentanyl patch?
As most Duragesic/Fentanyl patch patients know, the recommended procedure is to clean the area with water and then apply the patch. However, for anyone who has used Fentanyl Generics or Duragesic, we know that's ridiculous. Skin oil, patch location and hair are the 3 biggest adhesion factors for the patch adhesive to contend with.
Having used Duragesic 100mcg patches (x2 on occasion) for 13 years, I know of 4 good ways to keep the patch stuck:
1. If you're using Duragesic, Janssen Pharmaceuticals has long had a program for its Duragesic users who have this problem. They will send out free of charge 300 Bioclusive bandages (clear adhesive bandages) that will fit over the 100mcg patch. I've used them many times and they work well. You need to call them at the 800 number on the box. Only Duragesic users are eligible; you can get them online or order them at a pharmacy, but they're not cheap, around $100 a box.
Note: It's unclear as of 2013 whether or not Janssen still runs the Bioclusive program, but it's an automatic NO if you don't ask. You can of course just by them outright, but as I said, they're not cheap.
Worst case, you can always use medical tape to tape the edges of the patch.
2. Skin Prep - Skin Prep is a product made for Colostomy patients. It applies a thin film to the skin that helps the adhesive bond strongly to the skin. The tricky part is to only apply it to the skin area where the edges of the patch are going to be, since applying it to the transdermal area will block release of the drug. It works fantastic though, and most pharmacies carry it. They make 2 types, a lower cost one that stings, and a non-stinging one for double the cost. It doesn't sting that bad compared to the pain you're already dealing with.
2013 Note: Skin Prep works well with the older style patch type that used an adhesive edge and gel pocket, but it's impractical if you're using a patch such as the new Duragesic patches that are essentially a one-piece adhesive patch. Using SP will block the release of the Fentanyl.
3. Isopropyl Alcohol - all patch literature will tell you not to use Iso to clean the skin and then put the patch on. The reason for this is that Isopropyl leaves a residue on the skin that can interfere with the drug release. However, to get around that issue, clean the area with Iso, then rinse it with water to remove any residue and then dry well before applying. Iso is the only real way to get skin oil off of the skin, which is the primary reason the patch adhesive comes unbonded from the skin.
Of course if you use Grain alcohol (purchased from a liquor store), it leaves no residue.
The other reason is that Iso can cause skin irritation if not rinsed prior to the patch being applied.
4. Location, Location, Location - SRE (Skin Real Estate) is a major factor in how well your patch stays applied. The instructions tell you not to use the patch in the same spot over and over - this is to let the skin breathe between applications. It must be applied on the upper torso in order for the heart to properly distribute the drug throughout the body. I've always applied mine to my upper biceps, as the area is flat, relatively hairless, and the skin there doesn't flex like it does on the chest or elsewhere. Normally my regular dose is 1 100mcg patch, so I just switch arms every 2 days when I change it out for a new one. However, there have been times where I've needed 2 100mcg patches, and I have used them on both arms simultaneously. In those cases, I've overlapped the application by several hours so that the skin has time to breathe before reapplying. I also will apply it vertically or horizontally so that the same area isn't always completely covered. Edge scarring on the skin from the patch will occur, but it will go away in time if you stop using them.
If you're having difficulty with the patch staying applied and the area doesn't appear to have any hair, keep in mind that the small micro-hairs that we all have can interfere with the patch adhesive. In those cases, shave the area or use a hair remover / wax to ensure there's nothing to get in the way between the patch and your skin. Make sure you rinse it well with warm water and dry it well before you apply the patch though.
I know of terminal cancer patients who have required up to 6 100mcg patches, and in those cases they were applied on the back. The problem with that is you need someone to apply it, and if you're like me, you probably like doing it in private by yourself.
In a pinch, if your patch comes off, don't toss it. It's a misconception that it cannot be reapplied and used; as long as it doesn't stick to itself, you can re-use it, but if it does, of course you're out of luck. If you're using generics, you can buy Bioclusives yourself. Alternatively, simple transparent medical tape on the patch edges will keep the patch in place or help you to re-attach it. Make sure you clean the skin before reapplying, and put it in the same place. It takes about an hour, but if there's enough adhesive and medicine left, the body heat will start the drug release again.
When applying your patch after you've prepped the area, make sure you hold it between your hands for about a minute (BEFORE you remove the backing...) to warm and soften the adhesive. After you put it on, hold your hand over it for a minute to help the adhesive stick better
One other bit of advice - all doctors are required by Federal Law to only give a month's worth of Schedule 2 opiates to any patient, making us slaves to the system, and making it a real pain if a patch comes off and cannot be reused, especially if it was just applied recently. I learned early on to build up an emergency month supply of meds that will help me in such situations, or in those rare times where you have problems with medical insurance companies or prescription supply interruptions. It takes time, but most Fentanyl patients have breakthrough meds like Percocet. Use that to help you get by and try stretching your dosage in order to bank up extras so you don't fall short if a patch does get screwed up. If you're seeing a doctor that tells you to turn in any extras, get another one. Federal Law prohibits transfer of any narcotic to anyone other than whom it was prescribed for, and I know of no such exception for doctors, even prescribing ones. I have always been up front with my doctor about my emergency supply, and over the years he's been willing to give me a bit more when it's run low.
How long does a 100 mcg Fentanyl patch last?
It depends on the person and how long patches have been used, but in general you'll start feeling withdrawals around 6-8 hours after the patch dose expires. It takes another few days before it's really out of your system. If you've been using Fentanyl for a long time, it'll take days or weeks depending on how much and how long.
Is it safe to take trazodone and Fentanyl patch together?
You can, but they are typically not prescribed together since they perform the same function - long term dosage delivery of opiate for chronic pain. They can be prescribed together when the patient is making the transition from OxyContin to Duragesic or vice-versa, but there's really no reason for it. All Duragesic patches come with information instructing the patient and doctor on the minimum starting dosage with a morphine equivalence chart that allows them to estimate your current equivalence with the drug you're using to the equivalent Duragesic dosage. Janssen Pharmaceuticals does skew the dosage estimates lower than they normally should be though for safety reasons, since all patients should start at the lowest dose and then work up to maintenance levels.
The difference is in the time factor - OxyContin has an advertised dosage time of 12 hours effective dosage, while Fentanyl patches are good for either 48 to 72 hours depending on the individual. For most people it's 72 hours, but a small percentage of the population (myself included) only gets 48 hours.
Since they're both controlled delivery drugs, Fentanyl patches are often prescribed when OxyContin tolerance has lowered to the point where the patient is only getting relief for about the same time that an acute pain medication does - just over 6 hours. Before I started using Duragesic, I was barely getting 7 hours out of OxyContin. The idea in pain management is to maintain a controlled dosage with less medication at a steady rate over long periods so that the patient doesn't have to rely on more medication to achieve the same results. Of course as tolerance increases, dosages may have to be adjusted, or increased if the pain increases. I've had to do this several times over the many years I've used Duragesic, but ultimately was able to return to my normal dosage levels after the reason for increased need was dealt with.
the fentanyl patch is a long timed system patch in which it lasts up to 72 hours per patch and dosage in your system compared to the tablet of Oxycontin in which it only lasts about 6-8 hours per pill depending on dose and your tolerance of pain medications
What is Fentanyl 25mcg per hour?
This refers to a Fentanyl Transdermal patch, which is commonly used for chronic pain patients like myself that need continuous long-term opiate therapy. It is regulated by body heat, and is extremely effective.
There are several doses - 12.5, 25, 50, 75 and 100mcg patches, all of which can be used with one another to make specific dosages. For example, though my normal dose is 100mcg, I typically have to use 200mcg, so I'll use 2 100mcg patches.
Does Fentanyl show up in blood test for opiates?
Yes, Fentanyl will show up if they ask the lab to look for it or drugs of its category (opiates).
What is the peak of Fentanyl patch?
The peak of pain relief provided by the Fentanyl transdermal system is between 12 and 18 hours after application.
