Fentanyl

The amount of time it takes for the amount of drug in the body to reduce by 50% is called the half-life. It takes approximately five to six half lives for the drug to be cleared from the body. The half-life for fentanyl patches is 9.5 to 12.4 hours. Multiply that by 6 and it could take up to 74.4 hours to clear the drug. You can do the math. Fentanyl lozenges-approx. 7 hours.

Duragesic takes a few hours to kick in and is supposed to last up to 72 hours (like how Oxycontin is supposed to last 12 hours) but most people find it lasts 36-60 hours. From my experience I've found fentanyl patches to last about 48-54 hours. In regards to drug testing, assuming it's a UA, fentanyl takes longer to clear than most opiates, it would take AT LEAST 48 hours after the removal of the patch (assuming you wore it for at least 2 days)

100 mgs all at once will kill you. Only VERY slow releasing patches come in high doses. Injections and pills come in micrograms...usually 50 or 100. 100 miligrams given all at once is a fatal overdose.....by a lot.

Fentanyl is a narcotic that is used to manage pain in chronic pain sufferers, people with cancer, people with allergies to other pain medications and other pain related situations. Fentanyl is 50 to 100 times more potent than morphine. Hydromorphone or Dilaudid is 5 to 8 times more potent than morphine. Just to give you a comparison. The drug should not be taken recreationally and is highly addictive. I take it in patch form for my kidney condition and even after three years taking it I still get loads of side effects. Also you cannot just stop this cold turkey as you can die. I have gone to bed forgetting to replace the patch I removed after wearing for 72 hours, when I wake up less than 3-8 hours later I am curled in the fetal position, shaking and my whole body aches. Withdrawal is really bad. The upside however is that if this drug works for you it can be a good pain relief. In any case always ask your doctor first to see if you need narcotics and if fentanyl is right for you.

i smoked fent a few hours ago and just passed one of the higher quality home drug test for opiates (oxy, morph, vic...) no problem.

In a study of 7 patients given fentanyl in surgery -

Fentanyl and its two metabolites (norfentanyl and despropionylfentanyl) were extracted from samples and analyzed by gas chromatography/mass spectrometry.

Unchanged fentanyl was detectable in urine in all patients immediately postoperatively and in 3 of 7 patients at 24 hours.

By 72 hours, fentanyl was undetectable.

Norfentanyl was present in larger quantities than fentanyl immediately postoperatively and was detected in all patients at 48 hours and in 4 of 7 patients at 96 hours.

Fentanyl originally was developed as an anesthetic, and is still widely used today for surgical procedures where the patient needs to be conscious (relatively) and able to respond to commands (e.g., bronchoscopy). Fentanyl is 100 times more potent than morphine (100 micrograms of Fentanyl is equivalent to 10mg's of Morphine). Fentanyl patches (Duragesic, e.g.) use concentrated doses of Fentanyl delivered to the bloodstream transdermally over extended periods, which make them ideal for long term chronic pain patients.

minimum 50 cents micro-gram per hour 1 microgram is .001 milligrams

$85 bucks cash for a 100ng/hr patch is high price between 50-70 is reasonable. Cheaper sometimes in the midwest and out east.

When it is applied to the skin, lidocaine is released into the epidermal and dermal layers of the skin, reducing pain at the site of the dysfunctional nerves damaged by the prior herpes zoster infection

No. This can cause a potentially lethal overdose. Venlafaxine is a cytochrome P450 3A4 inhibitor which is the enzyme which metabolizes fentanyl. Levels of fentanyl can reach lethal doses as a result of this combination.

Yes you can, but like any drug you need to be aware of its effects on you, and how much more of a depressant effect it will have on you in addition to what you experience with Fentanyl. I've used Fiorinal w/ Codeine (Fiorinal uses aspirin rather than Tylenol, like Fioricet does) for over 20 years for Migraines, and have used 100mcg Fentanyl patches for about 9 years. The Butalbital in the Fiorinal is the only thing anymore that still makes me a bit drowsy - there are few things that can anymore with the amount of opiates I've had to take for so many years.

However, I'm highly tolerant to opiates and most depressants - it takes quite a bit to knock out most people who use Fentanyl on a regular basis, as Fentanyl is itself is used an an anesthetic normally. I'm also not a small person by any means - I'm 6' and 250 lbs.

Like with any drug you mix, it's always good to get your doctor's advice, since there may be other mitigating factors in your health that might preclude mixing the two. But as a general rule, there's no problem with using the two together, as they work a bit differently and on different areas of the body.

Patches that are applied should be maintained at body temp - any significant increase in temp can increase the dosage delivery rate.

For storage, maintain them in a cool, dry, dark place, below 77°F in their original foil packaging. If you've taken one off for later use (yes, you can do that if you maintain the edges), put it on the plastic backing and then wrap in tin foil.

Just like any opiate, you'll start feeling the withdrawal effects, but they're gradual, not like pills, happening over a couple of hours. Usually you'll start feeling cold/clammy first, then if you haven't replaced it in time, the rest of the usual withdrawal symptoms kick in.

You really should wait the 18 hours maybe an hour or two less If you can’t take it anymore. It’s really hard but REALLY worth it. I went into detox and on that 18th hour I was kicking my legs and jolting all over and just wanted to sleep and finally got a sub and within a half hour probably I fell asleep and I woke up feeling pretty well.

You don't want to have Fentanyl ;)

only when you need it, then it will make you sick for a day but pain free! or at least diminished to bearable.

I take 1/2 of 75mcg every 3rd day and just nod on the2nd day.

It makes my separated shoulder tolerable until it can be repaired in a few weeks.

I've been using these patches for several months now in different strenghs and have finally figured them out for me. when pain becomes constant and almost unbearable I dose up and await the next couple of days

Social Engineering attack

If it is specifically tested for, then Fentanyl will show up on a lab test. But they have to request for your urine to be tested for Fentanyl. On any 9 panel or 12 panel, no it doesn't show up.

You probably won't notice it (the Schedule IV version of codeine, what most people get, is pretty weak compared to Fentanyl) but it and similar lower-end opiates are used for breakthrough meds with Fentanyl patches.

can u shoot up non gel fentanyl patches

People do it all the tme....

Yes - as a synthesized opiate, Fentanyl is the strongest opiate available, and is 100x stronger than morphine.

It depends on the patient - by instruction, the patch must be applied on the upper torso or upper extremities (arms). Most people tend to put them on their back or chest, but I learned early on that for the back you need someone to change them, and the chest/stomach area has both too much hair and the skin flexes too much with activity.

As a result, for many years I've worn them on my biceps - they're flat, the patches easy to put on them with one hand, and the skin doesn't flex very much there. When using 1 100mcg patch, I just switch arms when it's time to put a new one on. When I have to increase to 2 100mcg patches, I use both arms, but take one off a few hours before the other to clean it and let the skin breathe before putting on a new one and taking the other one off. That way your dosage doesn't drop much during the process, and if you feel breakthrough you can take a Percocet or whatever your breakthrough med is to cover it.

The key to keeping a patch on (see the link to my answer on that below) is to make sure the skin is clean and there's no hair present. The literature says not to use any Isopropyl alcohol - that's because it leaves a residue. Problem is, it's difficult to remove skin oil and dirt without it. To get around the problem, clean it with Iso, then rinse the area well to make sure any residue is washed off. Dry the skin well, then apply the patch. If there's a lot of hair or micro-hairs, you might need to shave it off as well. Before you put the patch on, hold it between your hands (still attached to the backing) for about a minute to soften the adhesive. Apply it, then put your hand over it for another minute to ensure the adhesive gets a good bond to the skin. You'll find it sticks pretty well after that.

strong enought that if your arent opiate tolerant that the lowest dose of the patch will make you overdose, dont be stupid, when it says for opiate tollerent patients only it really facking means it.

No - they are 2 completely separate drugs. OxyContin is the time release version of Oxycodone, and typically lasts from 7-12 hours.

Duragesic / Fentanyl transdermal patches are timed release fentanyl over a 48-72 hour period. Its release is regulated by body heat. It is a much more reliable and steadier drug than OxyContin, in that it doesn't wear off as fast, and it lasts a lot longer.

The precursor used is N-Phenethyl-Piperidone (NPP) which can be easily synthesized from Piperidone and Phenethyl-tosylate or Phenethyl-bromide through a simple SN2 mechanism.The NPP is reacting with Aniline giving the Imine derivative which is reduced to the 4-Anilino-N-Phenethyl-Piperidine (4-ANPP). The 4-ANPP is then reacted with Propionyl Chloride giving Fentanyl which is then purified.