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Huntington's Disease
Huntington’s disease is a hereditary disorder that destroys certain areas of the brain involved in intellect, emotion, and movement development. It is characterized by the loss of mental abilities; developing of emotional problems; and uncontrollable movement of the limbs and face.
237 Questions
Is there are cure for huntingtons disease?
No, there is currently no cure for Huntingtons, but a neurologist is able to prescribe medication to patients with Huntingtons to help the suppress the symptoms. Researchers are currently looking into stem cell research for a cure.
What specific groups does huntington's disease affect?
Huntington's disease is a dominant genetic disease. That means that a person will develop the disorder if they receive one copy of the gene from an affected parent - so children with a parent who has Huntington's have a 50% chance of inheriting the gene and developing the disease. If children don't inherit the gene, however; they cannot pass it on to their own children. The chain of inheritance is broken.
Huntington's disease typically doesn't appear until the patient is between 30 and 50 years of age. Men and women are equally affected by the disease, and it crosses all racial and ethnic boundaries.
Can 2 people with Huntington's Disease produce an offspring who does not have Huntington's disease?
Unfortunately, no. Huntington's is carried on a dominant gene. One parent HD, one non-HD, you have a 50-50 chance of not inheriting that gene. But two parents that are HD, you will inherit the gene from one parent or the other.
Can you live if you have huntingtons disease?
Yes, Huntington's disease (know as HD) is a fatal neurological disease. HD is generally fatal within 20 years of symptoms first appearing. At this time (2011-03-20), there is no way to reverse or stop the course of HD, but research continues. In recent years, scientists have made a number of breakthroughs in this area. The future may well bring a cure.
PKU and T-S are generally diseases of children. In most cases, the symptoms of Huntington's appear gradually, usually starting after age 30. You can get more information on HD from the wesite for HDSA.
What is the end result of huntingtons disease?
At this time, there is no way to stop or reverse the course of Hunington's Disease. Huntington's disease results from genetically programmed degeneration of brain cells, called neurons, in certain areas of the brain. This degeneration causes uncontrolled movements, loss of intellectual faculties, and emotional disturbance. HD is a familial disease, passed from parent to child through a mutation in the normal gene. Each child of an HD parent has a 50-50 chance of inheriting the HD gene. If a child does not inherit the HD gene, he or she will not develop the disease and cannot pass it to subsequent generations. A person who inherits the HD gene will sooner or later develop the disease. Whether one child inherits the gene has no bearing on whether others will or will not inherit the gene. Some early symptoms of HD are mood swings, depression, irritability or trouble driving, learning new things, remembering a fact, or making a decision. As the disease progresses, concentration on intellectual tasks becomes increasingly difficult and the patient may have difficulty feeding himself or herself and swallowing.
What is the mutated allele that causes huntington's disease?
Autosomal and dominant. It's a defective gene on chromosome 4. :D Hope this helps!
How do people transmission Huntington's Disease?
There is actually no treatment for the condition of the disease once the symptoms start to appear on the patient's body. The patient will continue to experience mental and physical disablilties for life which makes it even more worse. The various types of medicines which are used will be adminstered but will not reverse the effects of the disease and the degeneration of the nerve cells. Drugs such as Tetrabenazine (Xenazine), tranquillizers like (clonazepam) and anti-psychotic drugs are used to treat the symptoms of the disease.
Hope this helps.
It depends on the two alleles the man carries; if he is carrying HH- it is a 100% chance, because HD is autosomal dominant. If his allele is Hh, it is a 50% chance.
When is the birth defect detected in Huntington's disease?
Huntington's disease is a progressive, degenerative disease that causes certain nerve cells in your brain to waste away. As a result, you may experience uncontrolled movements, emotional disturbances and mental deterioration.
Huntington's disease is an inherited disease. Signs and symptoms usually develop in middle age. Younger people with Huntington's disease often have a more severe case, and their symptoms may progress more quickly. Rarely, children may develop Huntington's disease.
Medications are available to help manage the signs and symptoms of Huntington's disease, but treatments can't prevent the physical and mental decline associated with the condition.
Is Huntington's disease a heterozygous genotype?
Most patients are heterozygous for the mutant copy of huntingtin however in some rare cases there are individuals who are homozygous for the disease-causing allele.
Homozygosity for the disease gene does NOT cause death at the embryo stage as the previous answer stated. Huntingtin null mice show embryonic lethality, but this is when they have no copies of the huntingtin gene at all. This is not the same as being mutant for the gene.
Individuals will have received one copy of the huntingtin gene from each of their parents and so the number of disease-causing CAG repeats will vary between each allele. If both copies have more than 35 repeats then they can be said to be homozygous for the mutant huntingtin allele. This seems to result in more severe symptoms and disease progression.
Transmitted by inheritance, it is a fatal progressive failure of the central nervous system. It affects voluntary and involuntary movement, memory, reasoning, and emotion. There is no cure, and limited treatment. Additional information is available at the website for the Huntington's Disease Association of America
How many people in the world have Huntington's disease?
About 30,000 people have been diagnosed with HD, and about 150,000 have a 50-50 risk if inheriting it. Those are the children of an HD positive parent that have not yet been tested for the disease.
same probable as the first child having it. By doing the punnet square, they are both recessive for the disease. There is a 25% chance that the child will get the disease.
Why is Huntington disease called Huntington's chorea?
This is because about 90% of people with HD have chorea. These movements may be mild at first, but can worsen and become more involuntary with time.
There are many organisations and support groups that can and will help you to cope with Huntington's disease. For more information about how to contact organisations and support groups worldwide, or for those in your part of the world, or for Internet support groups, please see the page links, further down this page, listed under Sources and Related Links.
