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Liver

The liver is a reddish brown gland that secretes digestive juices to aid in the digestion and absorption of food.

1,947 Questions

Where is the liver locate in your body?

It is located in theupper-right hand of abdominal cavity. It is beneath the diaphragm, and on the top of stomach. Posted By Samantha Wasinee Seeboonruang

Where in your body is your liver?

Your liver is almost right in the middle between your lungs and your stomach.

4 Why are patients with cirrhosis of the liver prone to developing upper gastrointestinal bleeding?

Because the blood coming through the portal vein cannot pass through the liver, it takes bypass routes (distended veins called varices) which happen to lie in the esophagus and stomach, where they may be eroded by stomach acid or swallowing abrasive stuff and bleed. Often such is bleed is catastrophic because their blood also clots less well, because the liver is in too bad a condition to make enough clotting factors.

What age group is impacted by a type of liver cancer called hepatoblastoma?

One type of primary liver cancer, called a hepatoblastoma, usually occurs in children younger than four years of age and between the ages of 12 and 15.

Anatomical term The liver is to the ---- of the stomach?

The correct anatomical term is \"The liver is to the right of the stomach\". It is the largest internal organ.

How many jobs does the liver do?

What does the liver do? The liver performs over 500 different functions! In fact it is so important that we cannot live without our liver. Maybe if you become a medical doctor you will learn all about them but right now we are going to look at the main things that the liver does. Let's look at the main three Your liver acts as a chemical processing factory to change most of the food that you eat into stuff that your body can use, and it gets rid of the things that are no use or are toxic (this word which means harmful to your body.) # Your liver makes bile which travels from the liver into the small intestine

Bile is a digestive juice which helps the body absorb fat from the gut into the bloodstream. The liver makes this thick, yellow-green substance then stores it in the gall bladder until the body needs some to digest fats.

# Your liver cleans your blood

Your liver takes toxins out of your blood. These may have been made by your body when breaking down proteins (say pro-teens), or been brought into your body through breathing or ingesting (say in-jest-ing) (this means taking into your body) something like alcohol, drugs or other harmful substances.

Your liver sorts things out and changes them chemically into what your body can use and turns what can't be used into something that dissolves in blood so that it can be carried to the kidneys. For example the liver makes urea (say you-rear) from parts of proteins that can't be used. It is poisonous so the body has to remove it. Blood collects this urea from the liver and sends it to the kidneys. They filter urea from the blood and it is then expelled from the body as waste in your urine. (See 'Your waste disposal system' if you want to know more about this.)

If you drink too much alcohol for a long time it can damage the liver so badly that it cannot do its job. This is called cirrhosis (say si-row-sis).

# Your liver makes and stores fuel

Your liver makes glucose from carbohydrates (say car-bow-hi-drates) that you eat, such as ones in bread, fruit and dairy products. Some of this glucose travels in blood to the rest of the body where it is used for energy.

Some of the glucose is stored in the liver as glycogen (say gly-co-jen) and it is there until your body needs to use extra energy, like when you have to run fast, react quickly or have to work your body hard for a long time.

It also helps to keep blood sugar at the right levels.

How does alcohol damage the liver?

It causes fatty tissue to build up in the liver, it suppresses enzymes needed to break down toxins in the body, and it causes scar tissue to form inside the liver (cirrhosis).

Why can the liver regenerate itself when none of the other major organs can?

ExplanationThe two following texts do answer the question, but in medically descriptive fashion.

The simplest explanation of "why" holds that natural selection has evolved an organ that is so critical to the body's functioning that, were it to fail, death would result.

Given the liver's criticality, and the fact that the body possesses a single liver, the liver also evolved the ability to regenerate. Mechanically complex organs (the heart) have not so far evolved such regenerative ability - perhaps natural selection can only go so far.

The clue to the liver's ability is homeostasis - "feedback" mechanisms that preserve function. Think of blood sugar - it has a desirable concentration which is regulated within narrow limits by insulin (to preserve the upper limit) and metabolisation of body fat and protein (to preserve the lower limit).

Now that we know "why", the answer for "none of the others can" - better asked as "none of the others were driven to" - is given by the existence of paired organs (lungs, kidneys, so we have a backstop), mechanical complexity (heart, too difficult) or "you-only-get-really-sick-and-die-but-it-often-happens-after-your-reproductive-peak" (pancreas, where diabetes can be survived for many years).

Remember that natural selection gets an organism to the point where it can reproduce - it "doesn't care" about old age - regrettably.

Medical descriptions.The liver is composed of a certain type of cells with increased ribosomal density, which mean the liver is the body's filter. We are all born with stem cells which are one of three types, Totipotent, pluripotent, or multipotent. The majority of stem remaining in humans after differtiaiton is multipotent cells, which have the tendency to become liver cells, so when lacking, the liver "recruits" some undiffertiated stem cells to become liver cells, and repair the liver.

The liver can precisely regulate its growth and mass. Surgical resection of hepatic lobes or hepatocyte loss caused by viral or chemical injury triggers hepatocyte replication while enlarged liver mass is corrected by apoptosis. Hepatocytes have a great replicative capacity and are capable of repopulating the liver. However, "stem-like" cells proliferate when hepatocyte replication is blocked or delayed. Detailed studies of the mechanisms that regulate liver growth have been done in animals subjected to partial hepatectomy or chemical injury. Substantial progress has been achieved using appropriate transgenic and knockout mouse models for this work. Gene expression in the regenerating liver can be divided into several phases, starting with expression of a large number of immediate early genes. Hepatocytes need to be primed before they can fully respond to the growth factors HGF (Hepatocyte Growth Factor), TGFα (Transforming Growth Factor Alpha), and EGF (Epidermal Growth Factor) in vitro. Priming requires the cytokines TNF and IL-6 in addition to other agents that prevent cytotoxicity. Reactive Oxygen Species and glutathione content can determine whether the TNF effect on hepatocytes is proliferative or apoptotic. At least four transcription factors, NFκB, STAT3 (which are strongly induced by TNF), AP-1 and C/EBPβ play major roles in the initiation of liver regeneration.
it is apparent that liver regeneration involves the interplay of mitogens and comitogens ,paracrine and autcrine process and cellular communications and miscommunications.there is no single instead group of events causes liver cell regeneration

Does chronic cholestasis require a liver transplant?

A liver transplant may become necessary if complications occur

What foods are good for dogs for liver and kidney?

Boiled chicken and any other white meat

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What is the real size of human liver?

By percussion (really means by tapping), the mean liver size is 7 cm for women and 10.5 cm for men. A liver that spans 2 to 3 cm larger or smaller than these values is considered abnormal. The liver weighs 1200 to 1400 g in the adult woman and 1400 to 1500 g in the adult man.

How many cm size of liver?

It is approximately 21-22.5 cm across its widest point, 15-17.5 cm at its greatest vertical height, and 10-12.5 cm from front to back.

What is Hemangioma Pericytoma?

a vascular tumor composed of spindle cells that are held to be derived from pericytes -- called also perithelioma

www.virtualtrials.com/dictionary.cfm

What connects the heart and liver?

From the Heart -> Liver: 1. first the aorta
2. then the hepatic artery


Liver -> Heart
1. Hepatic vein
2. Inferior vena cava

Is your liver an organ?

Although you cannot live without your liver, it is an accessory organ for the digestive system. For the digestive system it makes bile which helps to break down fats.

What is the difference between liver sclerosis and liver cirrhosis?

Sclerosis or cirrhosis as it is more commonly known is a disease that progresses to slowly effect the proper functioning of the liver. In this article, we try to tell you more about this disease, the causes for the same, its symptoms, the treatment process.

How would the histopathology department identify liver disease?

Histopathology is the study of the diseases of cells. So the histo department would examine cells from a liver biopsy to see what is causing the liver disease, the liver being made up of millions and millions of cells.

You have Raised cholesterol and elevated liver what could the causes be?

There are a number of possibilities. You should consult your doctor. Be sure to tell him accurately how much alcohol you drink.

What is sirrosis of the liver?

Liver cirrhosis is progressive scarring of the hepatocytes (liver cells), leading to loss of liver function. Cirrhosis is not a disease in itself- it is the term used for when a liver has become scarred beyond repair, due to any cause (whether viral, auto-immune, alcohol etc...). I.e it is the stage before "complete liver failure".

What happens to the function of lipase if bile salt production is reduced?

Lipase cannot function properly upon the substance it is attempting to digest without the help of bile which breaks down that substance. (in digestion the "substance" is any fats or lipids) This all occurs after leaving the stomach and entering the small intestine.