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Yes, in a couple of ways.

1) If you take them at the same time. Thyroid medications are meant to be taken alone, 30 minutes before you eat or digest anything else.

2) If aspirin (which is in Equate Extra Strength Headache relief) is used for even one week, the thyroid hormones they are looking for on tests (T3, T4 - both total and free, and TSH) will be lower. So, taking aspirin may not interfere with your thyroid medication, but it does interfere with how your thyroid is performing.

It should be noted that in some thyroid patients, specifically, those who have a normal thyroid except for low T3 or T4, taking thyroid hormones with acetaminophen can set you up for liver damage.

ibuprofen (Advil, Motrin) and Naproxen (Aleve) are safe alternative pain relievers which have not been shown to interfere with thyroid medications.

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Q: Does Equate Extra Strength Headache Relief interfere with thyroid medications?
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