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Acetylcholine binds to its receptor in the sarcolemma and triggers .?
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When acetylcholine diffuses across the synaptic cleft and binds to receptors on the folded sarcolemma it initaly causes what channels to open in the sarcolemma?
Chemically gated Na+ ions.
What is sarcolemma function?
These are the choices... a. Storage site for calcium ions in myofibersb. cell membrane of a myofiberc. compound that binds oxygen for use in slow, oxidative muscle cellsd. separation between sarcomeres in a myofibere structure that produces acetylcholine.
What receptor has a ligand that can cross the cell membrane that binds?
Intracellular
When a hormone molecule binds to a specific protein on the plasma membrane the protein it binds to is called?
... a receptor protein.
What binds to receptor molecules on the host cell membrane?
glycoproteins
When acetylcholine diffuses across the synaptic cleft and binds to receptors on the folded sarcolemma it initaly causes what channels to open in the sarcolemma?
Chemically gated Na+ ions.
What causes depolarisation of sarcolemma of muscle fibre?
An incoming action potential to an alpha motor neuron causes acetylcholine (Ach)release at the end plate, Ach binds to Ach receptors on the sarcolemma causing a sodium influx which causes depolarization.
What are chemical changes that are occurring during latent period?
Acetylcholine binds to sarcolemma; sarcolemma then T-tubules depolarize; Ca++ released from terminal cisternae travels along SR, is release into sarcoplasm, then binds to troponin to unblock tropomyosin binding sites allowing cross-bridge formation (i.e., myosin heads bind to actin).
What is agonsit?
An agonist is a chemical that binds to a receptor of a cell and triggers a response by the cell. An agonist often mimics the action of a naturally occurring substance.
What is sarcolemma function?
These are the choices... a. Storage site for calcium ions in myofibersb. cell membrane of a myofiberc. compound that binds oxygen for use in slow, oxidative muscle cellsd. separation between sarcomeres in a myofibere structure that produces acetylcholine.
Describe the interaction of acetylcholine and calcium ions in stimulating muscle contraction?
The acetylcholine diffuses across the synapse and binds to and activates nicotinic acetylcholine receptors on the motor end plate of the muscle cell. Activation of the nicotinic receptor opens its intrinsic sodium/potassium channel, causing sodium to rush in and potassium to trickle out.
What is a molecule that acts as signal when it binds to a receptor?
Intracellular receptor
What binds to a signal molecule enabling the cell to respond to the signal molecule?
receptor proteins bind to signal molecules
When a signal molecule binds to a receptor protein the receptor protein may change the?
shape.
What receptor has a ligand that can cross the cell membrane that binds?
Intracellular
The effect of a drug that is an agonist is to?
An agonist binds to a receptor and stimulates it (turns it on). An antagonist binds to a receptor and blocks it from being activated by other molecules (turns it off).
What binds acetylcholine and induces muscle contraction?
Acetylcholine is released at the neuromuscular junction and binds to a nicotinic receptor, causing an action potential to fire down the T tubules. The voltage change from this is sensed by the Sarcoplasmic Reticulum which then releases Ca2+ ions into the cytosol. The Ca2+ ions bind to troponin which moves tropomyosin from the active sites of the actin filament. Once the active sites are revealed, myosin quickly forms a cross bridge and begins contraction.
