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Acetylcholine binds to its receptors on the sarcolemma, leading to the opening of ion channels that allow sodium ions (Na+) to enter the muscle cell. This influx of sodium ions depolarizes the sarcolemma, generating an action potential. The action potential then travels along the T-tubules, ultimately triggering the release of calcium ions from the sarcoplasmic reticulum, which initiates muscle contraction.
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What happens when acetycholine binds to its receptor in the sarcolemma and triggers?
When acetylcholine binds to its receptor in the sarcolemma of a muscle cell, it triggers an action potential to be generated along the muscle cell membrane. This action potential then spreads along the sarcolemma and eventually leads to muscle contraction by initiating the release of calcium ions from the sarcoplasmic reticulum.
When acetylcholine diffuses across the synaptic cleft and binds to receptors on the folded sarcolemma it initaly causes what channels to open in the sarcolemma?
Acetylcholine binding causes nicotinic acetylcholine receptors on the folded sarcolemma to open, allowing the influx of sodium ions into the muscle cell. This initiates an action potential that propagates along the sarcolemma and into the T-tubules, triggering muscle contraction.
What change does ACh cause in an ACh receptor?
Acetylcholine (ACh) binding to an acetylcholine receptor triggers a conformational change in the receptor protein, leading to the opening of an ion channel within the receptor. This allows specific ions, such as sodium or potassium, to flow across the cell membrane, resulting in changes in membrane potential and ultimately leading to cellular responses.
What happens to ACh once it has bound to its receptor?
Once acetylcholine (ACh) binds to its receptor, it can either stimulate or inhibit the activity of the cell. This activation triggers a cellular response, such as muscle contraction or nerve cell communication. After its action, ACh is rapidly broken down by the enzyme acetylcholinesterase to terminate the signal.
What best describes how ACh changes the ion permeability of the sarcolemma?
Acetylcholine (ACh) binds to nicotinic receptors on the sarcolemma of muscle fibers, leading to the opening of ion channels. This results in an influx of sodium ions (Na+) into the cell, which depolarizes the sarcolemma and initiates an action potential. The change in ion permeability is crucial for muscle contraction, as it propagates the signal to the interior of the muscle fiber and ultimately stimulates the release of calcium ions from the sarcoplasmic reticulum.
What happens when acetycholine binds to its receptor in the sarcolemma and triggers?
When acetylcholine binds to its receptor in the sarcolemma of a muscle cell, it triggers an action potential to be generated along the muscle cell membrane. This action potential then spreads along the sarcolemma and eventually leads to muscle contraction by initiating the release of calcium ions from the sarcoplasmic reticulum.
Which neurotransmitter receptor is present on the sarcolemma?
Acetylcholine receptor is present on the sarcolemma of the muscle cells. This receptor is responsible for transmitting the signal to initiate muscle contraction when acetylcholine binds to it at the neuromuscular junction.
When acetylcholine diffuses across the synaptic cleft and binds to receptors on the folded sarcolemma it initaly causes what channels to open in the sarcolemma?
Acetylcholine binding causes nicotinic acetylcholine receptors on the folded sarcolemma to open, allowing the influx of sodium ions into the muscle cell. This initiates an action potential that propagates along the sarcolemma and into the T-tubules, triggering muscle contraction.
What change does ACh cause in an ACh receptor?
Acetylcholine (ACh) binding to an acetylcholine receptor triggers a conformational change in the receptor protein, leading to the opening of an ion channel within the receptor. This allows specific ions, such as sodium or potassium, to flow across the cell membrane, resulting in changes in membrane potential and ultimately leading to cellular responses.
What happens to ACh once it has bound to its receptor?
Once acetylcholine (ACh) binds to its receptor, it can either stimulate or inhibit the activity of the cell. This activation triggers a cellular response, such as muscle contraction or nerve cell communication. After its action, ACh is rapidly broken down by the enzyme acetylcholinesterase to terminate the signal.
What is a molecule such as a neurotransmitter or a hormone that binds to a receptor called?
A molecule such as a neurotransmitter or hormone that binds to a receptor is called a ligand. This binding triggers a biological response in the target cell, influencing its function.
What binds to a signal molecule enabling the cell to respond to the signal molecule?
A receptor protein on the cell membrane binds to the signal molecule, initiating a series of intracellular events that lead to a cellular response. The binding of the signal molecule to the receptor triggers a signaling cascade that ultimately activates specific cellular pathways.
Which of these activates an olfactory receptor and causes the transmission of information about a smell?
An odorant molecule binds to the olfactory receptor, which triggers a signaling cascade leading to the transmission of information about the smell to the brain.
What is agonsit?
An agonist is a chemical that binds to a receptor of a cell and triggers a response by the cell. An agonist often mimics the action of a naturally occurring substance.
The two neurotransmitters that affect smooth muscle cells are acetylcholine and?
norepinephrine. Acetylcholine mainly causes smooth muscle contraction, while norepinephrine can either cause contraction or relaxation depending on the type of receptor it binds to on the smooth muscle cell.
A ligand produces a response in a cell if it finds the right kind of?
receptor. When a ligand binds to its receptor on the cell surface or within the cell, it triggers a specific biological response or signaling pathway. The specificity of this interaction between ligand and receptor is critical in determining the cellular response.
Describe the interaction of acetylcholine and calcium ions in stimulating muscle contraction?
The acetylcholine diffuses across the synapse and binds to and activates nicotinic acetylcholine receptors on the motor end plate of the muscle cell. Activation of the nicotinic receptor opens its intrinsic sodium/potassium channel, causing sodium to rush in and potassium to trickle out.
