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DON'T DO IT! Technically you can, but Excedrin migrate has caffeine in it, enough that when I took it while on vyvanse, my heart was racing and I could not stop vommitting. If you can drink a bunch of coffee while on vyvanse, you probably won't have an issue with the Excedrin migrane, but be careful when taking too many stimulants at the same time.

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Q: Can you take excedrin migraine while taking Vyvanse?
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