Cholineesterase is enzyme that hydrolyses acetylcholine .
Cholinesterase inhibitors are drugs that block the activity of an enzyme in the brain called cholinesterase. Cholinesterase breaks apart the neurotransmitter acetylcholine, which is vital for the transmission of nerve impulses.
Acetylcholine
Acetylcholine
acetylcholine
a small organic molecule liberated at nerve endings as a neurotransmitter. It is particularly important in the stimulation of muscle tissue. The transmission of an impulse to the end of the nerve causes it to release neurotransmitter molecules onto the surface of the next cell, stimulating it. After such release, the acetylcholine is quickly broken into acetate and choline, which pass back to the first cell to be recycled into acetylcholine again. The poison curareacts by blocking the transmission of acetylcholine. Some nerve gases operate by preventing the breakdown of acetylcholine causing continual stimulation of the receptor cells, which leads to intense spasms of the muscles, including the heart. Acetylcholine is often abbreviated as Ach.
Decompose
Cholinesterase inhibitors are drugs that block the activity of an enzyme in the brain called cholinesterase. Cholinesterase breaks apart the neurotransmitter acetylcholine, which is vital for the transmission of nerve impulses.
It's an enzyme that breaks down the neurotransmitter acetylcholine. Basically, neurotransmitters are necessary for nerves to transmit impulses and messages throughout the body. Acetylcholine is used specifically to transmit sensory messages. Sometimes, the body produces so much acetylcholine that it becomes an annoyance. In these cases, cholinesterase is responsible for balancing out the production of acetylcholine by destroying it.
Electrical switching centers, called 'synapses' are found throughout the nervous systems of humans, other vertebrates, and insects. Muscles, glands, and nerve fibers called 'neurons' are stimulated or inhibited by the constant firing of signals across these synapses. Stimulating signals are usually carried by a chemical called 'acetylcholine' (a-see-till-ko-leen). Stimulating signals are discontinued by a specific type of cholinesterase enzyme, acetylcholinesterase, which breaks down the acetylcholine. These important chemical reactions are usually going on all the time at a very fast rate, with acetylcholine causing stimulation and acetylcholinesterase ending the signal. If cholinesterase-affecting insecticides are present in the synapses, however, this situation is thrown out of balance. The presence of cholinesterase inhibiting chemicals prevents the breakdown of acetylcholine. Acetylcholine can then build up, causing a "jam" in the nervous system. Thus, when a person receives to great an exposure to cholinesterase inhibiting compounds, the body is unable to break down the acetylcholine
Nerve agents work by blocking a hormone called cholinesterase. A nerve is basically a pipe. When your body wants to send information down a nerve, it puts a little bit of the hormone acetylcholine into it. When it wants to stop sending, it shoots some cholinesterase down the pipe, and the cholinesterase "turns off" the acetylcholine. (There's more to it than that, but you get the idea.) By stopping cholinesterase from working, your whole body just goes into convulsions and, eventually, you just seize up. Very nasty way to die.
Acetylcholine
A. G. Karczmar has written: 'Exploring the vertebrate cholinergic nervous system' -- subject(s): Cholinergic mechanisms, Vertebrates, Acetylcholine, Physiology 'Anticholinesterase agents' -- subject(s): Cholinesterase inhibitors
Acetylcholine (Ach), which causes sweat production
Acetylcholine
Activities of the cholinergic system are divided into two main categories: muscarinic and nicotinic. Both actions involve modulation of pain perception. Anything which increases the presence of Acetylcholine in the synaptic space is found to produce analgesia. Neostigmine and donepezil being cholinesterase inhibitors are used in pain relief because of increasing acetylcholine in synapses through this action. Benzodiazepines act as analgesics through their action of enhancing Ach release.
Acetylcholine (ACh)
most notably a class of drugs called cholinesterase inhibitors . These medications tend to increase a brain neurochemical called acetylcholine, which is an excitatory brain chemical that is decreased in persons with LBD