Catabolite repression is the positive control of the lactose operon in bacteria. Glucose is metabolized initially and when depleted, the lactose.
Bacteria preferentially utilize lactose as a carbon source.
its an operon required for the transport and metabolism of lactose.
lactose metabolizing enzymes need not be made when lactose is not present.
The lac repressor protein has a binding site for lactose itself.
The lac operon encodes enzymes required in the digestion and transport of lactose. Transcription is activated when there is lactose in the cellular environment, and RNA polymerase binds to the promoter region of the operon, and activates the expression of lacA, lacZ and lacY.
Bacteria preferentially utilize lactose as a carbon source.
its an operon required for the transport and metabolism of lactose.
Because it is normally inhibited and needs a precursor molecule to release the inhibitory molecule so that the bacteria can metabolize lactose. Induced.
The lac operon is most active when glucose levels are low and lactose is present.
When the lac operon controls the expression of proteins in the E.coli cell that can break down lactose into two sugars, glucose and galactose. When lactose is present, it binds to the repressor that typically sits on the lac operon, changing the repressor's conformation such that it can no longer bind to the lac operon. Because of this, RNA polymerase can now transcribe the gene into mRNA, which in turn is translated into the proteins that can break down lactose.
the coordinated control of gene expression in bacteria
lactose metabolizing enzymes need not be made when lactose is not present.
Lactose is present, otherwise the lac operon is not needed and is shut off.
1. in lac operon; gene activity is induced when lactose is present in the medium, whereas in case of trp operon, repression of the gene activity takes place in presence of tryptophan in the medium. 2. lac operon spans about 4-6kb...whereas trp operon spans abut 7kb. 3. lac operon helps in the breakdown of lactose into glucose and galactose, to generate energy( catabolic pathway ) in case of trp operon, it helps in the synthesis of enzymes required for the formation of the amino acid Tryptophan( anabolic pathway ). 4. lac operon is an example of positive regulation ; and trp operon is an example of negative regulation. Trp operon is also regulated by other mechanism called attenuation while no such even occurs in lac operon . .
E. coli binds with lactose which changes its conformation so that it no longer binds to DNA. This allows the lactose operon to be transcribed.
The lac operon is most active when glucose levels are low and lactose is present.
it is by lac operon syastem